ectonucleotide pyrophosphatase/phosphodiesterase 7

 jump to detail

Synonym

NPP-7, MGC50179, alk-SMase, Intestinal alkaline sphingomyelinase, Alkaline sphingomyelin phosphodiesterase, ectonucleotide pyrophosphatase/phosphodiesterase 7, UNQ3077/PRO9912, Alk-SMase, E-NPP7, ENPP7, ALK-SMase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.02 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.01 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:0 stomach:- intestine:4.97 colon:1.98     liver/hepato:1.29    lung:0 bladder:0 kidney:0.44 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0.01 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0.02     liver/hepato:1.19        lung:0    bladder:- kidney:0.42 pituitary:- thyroid/parathyroid:0 adrenal gland:0.10 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_178543
Gene ID 339221
Unigene ID Hs.114084
Probe set ID -
Ensembl ID ENSG00000182156
GTEx ID ENSG00000182156

Orthologous Gene

Mouse[1]  NM_001030291
Rat[1]  NM_001030291

Chromosomal Region

17q25.3  [77,704,882  -  77,716,020]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

12477932
12671034
12885774
12975309
14702039
15016655
15340161
15458386
15489334
15708357
16255717
16344560
19850743
20839774
22177013

Gene Ontology  (GO ID)

Biological Process

GO:0006687  glycosphingolipid metabolic process
GO:0008285  negative regulation of cell proliferation
GO:0008156  negative regulation of DNA replication
GO:0006665  sphingolipid metabolic process
GO:0006684  sphingomyelin metabolic process

Cellular Component

GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005902  microvillus
GO:0005886  plasma membrane

Molecular Function

GO:0004767  sphingomyelin phosphodiesterase activity