isocitrate dehydrogenase 3 (NAD+) gamma

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Synonym

IDH3G, isocitrate dehydrogenase 3 (NAD+) gamma, H-IDHG

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:69.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:336.90 retina:- eye:117.50 artery/aorta:30 vein:- lymphnode:30.30 peripheral blood:109.30 spleen:18.90 thymus:12.90 bone marrow:59 adipose:- bone:89.60 skin:43.20
GeneChip cerebrum:7.66 cerebellum:7.49 brain stem:7.73 corpus callosum/glia:7.09 pineal gland:- peripheral nerve:7.64 spine:7.12 retina:- eye:- artery/aorta:7.73 vein:7.58 lymphnode:7.37 peripheral blood:- spleen:7.07 thymus:7.70 bone marrow:6.91 adipose:7.46 bone:- skin:7.76
CAGE cerebrum:4.55 cerebellum:- brain stem:4.39 corpus callosum/glia:4.30 pineal gland:3.92 peripheral nerve:- spine:4.15 retina:- eye:- artery/aorta:4.48 vein:4.54 lymphnode:4.20 peripheral blood:- spleen:4.24 thymus:4.30 bone marrow:- adipose:4.21 bone:- skin:-
RNA-seq cerebrum:0.52 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.69 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.85 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:61.90 prostate:33.80 ovary:111.80 testis:38.90 heart:76.60 muscle:40.20 esophagus:- stomach:63.70 intestine:- colon:110.20     liver/hepato:-        lung:48.90    bladder:- kidney:41.60 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:529.70 salivary:-
GeneChip uterus:7.50 placenta:6.98 prostate:7.70 ovary:7.46 testis:7.44 heart:7.48 muscle:7.80 esophagus:7.68 stomach:6.98 intestine:7.47 colon:7.56 liver/hepato:6.70 lung:7.30 bladder:- kidney:7.86 pituitary:7.38 thyroid/parathyroid:7.33 adrenal gland:7.26 pancreas:6.96 breast:7.54 salivary:7.45
CAGE uterus:4.19 placenta:4.05 prostate:4.13 ovary:4.32 testis:3.96 heart:4.29 muscle:4.64 esophagus:4.12 stomach:- intestine:4.54 colon:4.28     liver/hepato:4.24    lung:4.00 bladder:3.96 kidney:4.68 pituitary:3.84 thyroid/parathyroid:4.08 adrenal gland:- pancreas:4.62 breast:3.95 salivary:4.70
RNA-seq uterus:- placenta:- prostate:0.82 ovary:1.47 testis:0.80 heart:0.50 muscle:0.31 esophagus:- stomach:- intestine:- colon:0.78     liver/hepato:0.44        lung:1.24    bladder:- kidney:1.45 pituitary:- thyroid/parathyroid:1.77 adrenal gland:1.92 pancreas:- breast:1.05 salivary:-

Gene Information

IDs

Refseq ID NM_174869
Gene ID 3421
Unigene ID Hs.410197
Probe set ID 202471_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000067829
GTEx ID ENSG00000067829

Orthologous Gene

Mouse[2]  NM_008323
Rat [0]  

Chromosomal Region

Xq28  [153,051,221  -  153,059,978]

Gene Family (Interpro ID)

IPR004434  Isocitrate dehydrogenase NAD-dependent, mitochondrial
IPR001804  Isocitrate/isopropylmalate dehydrogenase

Link to Pubmed  (Pubmed ID)

8661155
9286695
10601238
10677231
11076863
11181995
11256614
12477932
14555658
15489334
15489336
16381901
16737955
17314511
17432878
18029348
22939629
23798571

Gene Ontology  (GO ID)

Biological Process

GO:0005975  carbohydrate metabolic process
GO:0044237  cellular metabolic process
GO:0006102  isocitrate metabolic process
GO:0006099  tricarboxylic acid cycle

Cellular Component

GO:0005759  mitochondrial matrix
GO:0005739  mitochondrion
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0004449  isocitrate dehydrogenase (NAD+) activity
GO:0000287  magnesium ion binding
GO:0051287  NAD or NADH binding