aquaporin 2 (collecting duct)

Synonym

ADH water channel, Water channel protein for renal collecting duct, AQP-CD, AQP-2, AQP2, Aquaporin-2, MGC34501, Aquaporin-CD, Collecting duct water channel protein, aquaporin 2 (collecting duct), WCH-CD

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:2.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:17.60

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:5.74

cerebellum:5.75

brain stem:5.75

corpus callosum/glia:5.73

pineal gland:-

peripheral nerve:5.71

spine:5.74

retina:-

eye:-

artery/aorta:6.01

vein:5.84

lymphnode:5.58

peripheral blood:-

spleen:5.54

thymus:5.64

bone marrow:5.99

adipose:5.75

bone:-

skin:5.85

CAGE

cerebrum:0

cerebellum:-

brain stem:0

corpus callosum/glia:0

pineal gland:0

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:0

vein:0.18

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.20

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:123.90

ovary:-

testis:4.30

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:8.50

liver/hepato:-

lung:14.70

bladder:-

kidney:353.50

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:5.52

placenta:5.82

prostate:5.64

ovary:5.61

testis:5.61

heart:5.63

muscle:5.76

esophagus:5.60

stomach:5.57

intestine:5.72

colon:5.74

liver/hepato:5.66

lung:5.72

bladder:-

kidney:8.15

pituitary:5.95

thyroid/parathyroid:5.58

adrenal gland:5.78

pancreas:6.22

breast:5.55

salivary:5.59

CAGE

uterus:0.13

placenta:0

prostate:2.84

ovary:0

testis:1.44

heart:0.71

muscle:0

esophagus:0

stomach:-

intestine:0

colon:0

liver/hepato:0

lung:0

bladder:1.49

kidney:5.54

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:3.89

ovary:0.00

testis:2.41

heart:0.00

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0

liver/hepato:0

lung:0.04

bladder:-

kidney:7.71

pituitary:-

thyroid/parathyroid:0.01

adrenal gland:0.02

pancreas:-

breast:0.05

salivary:-

IDs

Refseq ID	NM_000486
Gene ID	359
Unigene ID	Hs.130730
Probe set ID	206672_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000167580
GTEx ID	ENSG00000167580

Orthologous Gene

Mouse[1]	NM_009699
Rat [0]

Chromosomal Region

12q13.12 [50,344,524 - 50,352,664]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR012269	Aquaporin
IPR000425	Major intrinsic protein

Gene Ontology (GO ID)

Biological Process

GO:0030042	actin filament depolymerization
GO:0007568	aging
GO:0006915	apoptosis
GO:0006884	cell volume homeostasis
GO:0071280	cellular response to copper ion
GO:0071288	cellular response to mercury ion
GO:0042631	cellular response to water deprivation
GO:0007588	excretion
GO:0007565	female pregnancy
GO:0015793	glycerol transport
GO:0006972	hyperosmotic response
GO:0051928	positive regulation of calcium ion transport
GO:0003097	renal water transport
GO:0051592	response to calcium ion
GO:0033762	response to glucagon stimulus
GO:0032496	response to lipopolysaccharide
GO:0010226	response to lithium ion
GO:0009651	response to salt stress
GO:0042594	response to starvation
GO:0055085	transmembrane transport
GO:0006833	water transport

Cellular Component

GO:0016324	apical plasma membrane
GO:0016323	basolateral plasma membrane
GO:0030136	clathrin-coated vesicle
GO:0005769	early endosome
GO:0070382	exocytic vesicle
GO:0005794	Golgi apparatus
GO:0016021	integral to membrane
GO:0005764	lysosome
GO:0005886	plasma membrane
GO:0043234	protein complex
GO:0055037	recycling endosome
GO:0005791	rough endoplasmic reticulum
GO:0005802	trans-Golgi network
GO:0030658	transport vesicle membrane

Molecular Function

GO:0003779	actin binding
GO:0015168	glycerol transmembrane transporter activity
GO:0030165	PDZ domain binding
GO:0015250	water channel activity
GO:0005372	water transporter activity

aquaporin 2 (collecting duct)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function