potassium voltage-gated channel, Shaw-related subfamily, member 1

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Synonym

NGK2, Voltage-gated potassium channel subunit Kv3.1, MGC129855, Kv4, KV3.1, KCNC1, KV4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:20.10 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.87 cerebellum:8.36 brain stem:7.01 corpus callosum/glia:5.28 pineal gland:- peripheral nerve:5.88 spine:6.18 retina:- eye:- artery/aorta:5.04 vein:5.20 lymphnode:4.96 peripheral blood:- spleen:4.90 thymus:4.77 bone marrow:5.17 adipose:5.34 bone:- skin:5.28
CAGE cerebrum:4.16 cerebellum:- brain stem:2.84 corpus callosum/glia:2.32 pineal gland:3.46 peripheral nerve:- spine:2.50 retina:- eye:- artery/aorta:0.34 vein:0.18 lymphnode:0.03 peripheral blood:- spleen:0.09 thymus:0.06 bone marrow:- adipose:0.36 bone:- skin:-
RNA-seq cerebrum:3.35 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:4.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.88 placenta:5.46 prostate:4.89 ovary:4.60 testis:5.74 heart:5.37 muscle:5.62 esophagus:5.13 stomach:5.32 intestine:5.13 colon:5.37 liver/hepato:5.24 lung:4.88 bladder:- kidney:5.34 pituitary:5.73 thyroid/parathyroid:4.88 adrenal gland:5.21 pancreas:5.40 breast:4.83 salivary:5.22
CAGE uterus:0.58 placenta:0 prostate:0 ovary:0 testis:1.52 heart:0.09 muscle:0.49 esophagus:0 stomach:- intestine:0.14 colon:0.18     liver/hepato:0    lung:0 bladder:0.18 kidney:0 pituitary:2.09 thyroid/parathyroid:0.06 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.02 ovary:0.00 testis:0.17 heart:0.01 muscle:0 esophagus:- stomach:- intestine:- colon:0.04     liver/hepato:0.03        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0 pancreas:- breast:0.03 salivary:-

Gene Information

IDs

Refseq ID NM_001112741
Gene ID 3746
Unigene ID Hs.552896
Probe set ID 208477_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000129159
GTEx ID ENSG00000129159

Orthologous Gene

Mouse[2]  NM_001112739, NM_008421
Rat[1]  NM_012856, NM_008421

Chromosomal Region

11p15.1  [17,756,359  -  17,804,602]

Gene Family (Interpro ID)

IPR011333  BTB/POZ fold
IPR000210  BTB/POZ-like
IPR003968  Potassium channel, voltage dependent, Kv
IPR003974  Potassium channel, voltage dependent, Kv3
IPR005403  Potassium channel, voltage dependent, Kv3.1
IPR003971  Potassium channel, voltage dependent, Kv9
IPR003091  Voltage-dependent potassium channel

Link to Pubmed  (Pubmed ID)

1400413
7559593
8449507
12060745
12477932
12805291
14702039
16344560
16382104
19213956
19332619
19913121
20628086
21106837
21912965
21945320
22387313
23576435
24143882

Gene Ontology  (GO ID)

Biological Process

GO:0006813  potassium ion transport
GO:0051260  protein homooligomerization
GO:0007268  synaptic transmission

Cellular Component

GO:0005886  plasma membrane
GO:0008076  voltage-gated potassium channel complex

Molecular Function

GO:0005251  delayed rectifier potassium channel activity
GO:0005249  voltage-gated potassium channel activity