LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

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Synonym

lunatic fringe (Drosophila) homolog, LFNG, SCDO3, lunatic fringe homolog (Drosophila)

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:5.90 artery/aorta:30 vein:- lymphnode:10.10 peripheral blood:18.20 spleen:- thymus:12.90 bone marrow:- adipose:- bone:- skin:9.60
GeneChip cerebrum:4.52 cerebellum:4.43 brain stem:4.67 corpus callosum/glia:4.44 pineal gland:- peripheral nerve:3.97 spine:4.21 retina:- eye:- artery/aorta:4.48 vein:4.67 lymphnode:4.46 peripheral blood:- spleen:4.10 thymus:4.13 bone marrow:4.65 adipose:4.60 bone:- skin:4.59
CAGE cerebrum:3.14 cerebellum:- brain stem:3.00 corpus callosum/glia:3.45 pineal gland:3.15 peripheral nerve:- spine:3.56 retina:- eye:- artery/aorta:3.53 vein:4.05 lymphnode:3.91 peripheral blood:- spleen:3.30 thymus:2.67 bone marrow:- adipose:3.21 bone:- skin:-
RNA-seq cerebrum:0.15 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.05 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.21 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:10.90 prostate:22.50 ovary:- testis:- heart:12.80 muscle:- esophagus:- stomach:- intestine:32.40 colon:33.90     liver/hepato:-        lung:9.80    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.38 placenta:4.15 prostate:4.32 ovary:4.45 testis:4.12 heart:4.51 muscle:4.74 esophagus:4.46 stomach:4.33 intestine:4.57 colon:4.69 liver/hepato:4.44 lung:4.44 bladder:- kidney:4.27 pituitary:4.41 thyroid/parathyroid:4.23 adrenal gland:4.41 pancreas:4.98 breast:4.24 salivary:4.60
CAGE uterus:3.63 placenta:2.84 prostate:3.63 ovary:2.32 testis:2.43 heart:2.62 muscle:1.73 esophagus:3.11 stomach:- intestine:3.17 colon:4.15     liver/hepato:1.41    lung:3.91 bladder:3.18 kidney:2.09 pituitary:0.50 thyroid/parathyroid:1.87 adrenal gland:- pancreas:4.85 breast:3.83 salivary:3.27
RNA-seq uterus:- placenta:- prostate:1.02 ovary:0.06 testis:0.19 heart:0.27 muscle:0.27 esophagus:- stomach:- intestine:- colon:0.16     liver/hepato:0.00        lung:1.05    bladder:- kidney:0.40 pituitary:- thyroid/parathyroid:0.19 adrenal gland:0.90 pancreas:- breast:0.88 salivary:-

Gene Information

IDs

Refseq ID NM_001040167
Gene ID 3955
Unigene ID Hs.159142
Probe set ID 215270_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000106003
GTEx ID ENSG00000106003

Orthologous Gene

Mouse[2]  NM_008494
Rat[1]  NM_133393

Chromosomal Region

7p22.3  [2,552,163  -  2,568,811]

Gene Family (Interpro ID)

IPR017374  Fringe
IPR003378  Fringe-like

Link to Pubmed  (Pubmed ID)

9187150
9878264
10341080
10935626
11346656
12110169
12477932
12486116
14702039
16341674
16385447
19020755
19061953
20301533
20301771
21832049
22624713
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0007386  compartment specification
GO:0007143  female meiosis
GO:0007219  Notch signaling pathway
GO:0009887  organ morphogenesis
GO:0001541  ovarian follicle development
GO:0045747  positive regulation of Notch signaling pathway
GO:0032092  positive regulation of protein binding

Cellular Component

GO:0005576  extracellular region
GO:0030173  integral to Golgi membrane

Molecular Function

GO:0046872  metal ion binding
GO:0003674  molecular_function
GO:0033829  O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity