ligase I, DNA, ATP-dependent

Synonym

Polydeoxyribonucleotide synthase [ATP] 1, MGC130025, LIG1, MGC117397, DNA ligase 1, DNA ligase I, ligase I, DNA, ATP-dependent

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:34.40

cerebellum:88.20

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:118.60

eye:47

artery/aorta:119.90

vein:-

lymphnode:60.70

peripheral blood:18.20

spleen:37.80

thymus:167.50

bone marrow:39.40

adipose:40.30

bone:12.80

skin:28.80

GeneChip

cerebrum:5.67

cerebellum:5.72

brain stem:5.93

corpus callosum/glia:5.83

pineal gland:-

peripheral nerve:5.62

spine:5.72

retina:-

eye:-

artery/aorta:5.81

vein:5.58

lymphnode:6.67

peripheral blood:-

spleen:6.22

thymus:7.34

bone marrow:7.19

adipose:5.82

bone:-

skin:6.37

CAGE

cerebrum:2.64

cerebellum:-

brain stem:2.58

corpus callosum/glia:2.62

pineal gland:2.54

peripheral nerve:-

spine:2.87

retina:-

eye:-

artery/aorta:2.22

vein:3.18

lymphnode:3.24

peripheral blood:-

spleen:2.63

thymus:3.96

bone marrow:-

adipose:1.88

bone:-

skin:-

RNA-seq

cerebrum:1.39

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.99

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.16

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:58.30

prostate:45.10

ovary:37.30

testis:82.20

heart:51.10

muscle:-

esophagus:-

stomach:42.50

intestine:-

colon:93.30

liver/hepato:42.20

lung:34.20

bladder:-

kidney:10.40

pituitary:116

thyroid/parathyroid:-

adrenal gland:-

pancreas:53.30

breast:46.50

salivary:-

GeneChip

uterus:6.01

placenta:6.35

prostate:6.05

ovary:6.18

testis:6.84

heart:5.25

muscle:5.53

esophagus:6.19

stomach:5.95

intestine:6.13

colon:6.12

liver/hepato:5.89

lung:5.91

bladder:-

kidney:5.66

pituitary:6.31

thyroid/parathyroid:6.43

adrenal gland:5.64

pancreas:5.95

breast:6.39

salivary:5.69

CAGE

uterus:2.66

placenta:3.06

prostate:2.31

ovary:2.48

testis:2.90

heart:1.56

muscle:1.70

esophagus:2.42

stomach:-

intestine:2.73

colon:2.83

liver/hepato:1.99

lung:2.47

bladder:1.71

kidney:1.96

pituitary:2.56

thyroid/parathyroid:2.10

adrenal gland:-

pancreas:2.54

breast:2.19

salivary:2.50

RNA-seq

uterus:-

placenta:-

prostate:1.66

ovary:2.13

testis:2.71

heart:0.49

muscle:1.16

esophagus:-

stomach:-

intestine:-

colon:0.60

liver/hepato:0.85

lung:1.50

bladder:-

kidney:1.34

pituitary:-

thyroid/parathyroid:2.20

adrenal gland:2.38

pancreas:-

breast:1.32

salivary:-

IDs

Refseq ID	NM_000234
Gene ID	3978
Unigene ID	Hs.1770
Probe set ID	202726_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000105486
GTEx ID	ENSG00000105486

Orthologous Gene

Mouse[4]	NM_001083188, NM_001199310, NM_010715
Rat[2]	NM_001024268, NM_030855, NM_010715

Chromosomal Region

19q13.33 [48,618,703 - 48,673,601]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR012310

ATP dependent DNA ligase, central

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0009653	anatomical structure morphogenesis
GO:0006284	base-excision repair
GO:0051301	cell division
GO:0051103	DNA ligation during DNA repair
GO:0006259	DNA metabolic process
GO:0006281	DNA repair
GO:0006271	DNA strand elongation during DNA replication
GO:0006302	double-strand break repair
GO:0000724	double-strand break repair via homologous recombination
GO:0006303	double-strand break repair via nonhomologous end joining
GO:0006273	lagging strand elongation
GO:0000278	mitotic cell cycle
GO:0006289	nucleotide-excision repair
GO:0006297	nucleotide-excision repair, DNA gap filling
GO:0042542	response to hydrogen peroxide
GO:0000723	telomere maintenance
GO:0000722	telomere maintenance via recombination
GO:0032201	telomere maintenance via semi-conservative replication
GO:0006283	transcription-coupled nucleotide-excision repair
GO:0033151	V(D)J recombination

Cellular Component

GO:0005694	chromosome
GO:0005739	mitochondrion
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0005524	ATP binding
GO:0003677	DNA binding
GO:0003910	DNA ligase (ATP) activity
GO:0003909	DNA ligase activity
GO:0046872	metal ion binding

ligase I, DNA, ATP-dependent

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function