pim-3 oncogene

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Synonym

pim-3, Serine/threonine-protein kinase Pim-3, pim-3 oncogene, PIM3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:26.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:88.20 artery/aorta:- vein:133.30 lymphnode:151.70 peripheral blood:72.90 spleen:18.90 thymus:12.90 bone marrow:59 adipose:40.30 bone:38.40 skin:24
GeneChip nodata
CAGE cerebrum:3.09 cerebellum:- brain stem:3.53 corpus callosum/glia:3.33 pineal gland:2.73 peripheral nerve:- spine:3.49 retina:- eye:- artery/aorta:4.12 vein:3.76 lymphnode:4.00 peripheral blood:- spleen:4.11 thymus:2.95 bone marrow:- adipose:4.45 bone:- skin:-
RNA-seq cerebrum:2.58 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.88 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:61.90 prostate:45.10 ovary:37.30 testis:64.90 heart:25.50 muscle:40.20 esophagus:- stomach:63.70 intestine:32.40 colon:25.40     liver/hepato:10.60        lung:83.10    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:133.40 breast:9.30 salivary:-
GeneChip nodata
CAGE uterus:3.62 placenta:4.21 prostate:4.28 ovary:3.57 testis:3.46 heart:3.78 muscle:3.92 esophagus:4.09 stomach:- intestine:3.86 colon:4.01     liver/hepato:3.92    lung:4.72 bladder:4.16 kidney:4.22 pituitary:2.89 thyroid/parathyroid:3.75 adrenal gland:- pancreas:3.89 breast:4.80 salivary:4.34
RNA-seq uterus:- placenta:- prostate:4.96 ovary:3.10 testis:3.87 heart:3.16 muscle:4.89 esophagus:- stomach:- intestine:- colon:3.69     liver/hepato:4.11        lung:5.92    bladder:- kidney:4.39 pituitary:- thyroid/parathyroid:4.42 adrenal gland:4.85 pancreas:- breast:3.88 salivary:-

Gene Information

IDs

Refseq ID NM_001001852
Gene ID 415116
Unigene ID Hs.530381
Probe set ID -
Ensembl ID ENSG00000198355
GTEx ID ENSG00000198355

Orthologous Gene

Mouse[4]  NM_145478
Rat[4]  NM_145478

Chromosomal Region

22q13.33  [50,354,161  -  50,357,728]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

10713710
12477932
12798037
15199164
15489334
15540201
16403219
17270021
18593906
19154409
19266083
19624871
20101231
20939820
21187426
21297633
21646687
21668797
21870113
21906983
21963094
22053931
22939624
23209281
23760491
23845873
24488669

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0007049  cell cycle
GO:0016572  histone phosphorylation
GO:0043066  negative regulation of apoptosis
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0007346  regulation of mitotic cell cycle

Cellular Component

GO:0005737  cytoplasm

Molecular Function

GO:0005524  ATP binding
GO:0005515  protein binding
GO:0004674  protein serine/threonine kinase activity