MyoD family inhibitor

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Synonym

MyoD family inhibitor, I-MF, Myogenic repressor I-mf, MDFI

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:9.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:29.40 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:9.60
GeneChip cerebrum:5.77 cerebellum:6.03 brain stem:5.89 corpus callosum/glia:5.73 pineal gland:- peripheral nerve:5.44 spine:5.56 retina:- eye:- artery/aorta:5.73 vein:5.89 lymphnode:5.68 peripheral blood:- spleen:5.22 thymus:5.15 bone marrow:5.85 adipose:6.28 bone:- skin:5.86
CAGE cerebrum:0.73 cerebellum:- brain stem:0.83 corpus callosum/glia:1.04 pineal gland:0.91 peripheral nerve:- spine:0.78 retina:- eye:- artery/aorta:1.61 vein:2.20 lymphnode:2.09 peripheral blood:- spleen:0.39 thymus:0.28 bone marrow:- adipose:2.12 bone:- skin:-
RNA-seq cerebrum:0.46 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.22 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.30 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:36.40 prostate:11.30 ovary:74.50 testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:39.10    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip uterus:5.72 placenta:5.90 prostate:5.52 ovary:5.97 testis:5.53 heart:6 muscle:6 esophagus:6.58 stomach:5.70 intestine:5.81 colon:5.93 liver/hepato:5.81 lung:5.83 bladder:- kidney:5.72 pituitary:5.62 thyroid/parathyroid:5.44 adrenal gland:5.80 pancreas:5.95 breast:5.75 salivary:5.99
CAGE uterus:1.98 placenta:2.63 prostate:2.41 ovary:2.50 testis:1.40 heart:1.32 muscle:0.13 esophagus:2.71 stomach:- intestine:0.33 colon:1.17     liver/hepato:0.84    lung:2.29 bladder:1.98 kidney:0.67 pituitary:1.17 thyroid/parathyroid:1.75 adrenal gland:- pancreas:0 breast:0.90 salivary:1.00
RNA-seq uterus:- placenta:- prostate:2.21 ovary:3.33 testis:2.42 heart:0.12 muscle:0.03 esophagus:- stomach:- intestine:- colon:0.69     liver/hepato:0.09        lung:3.49    bladder:- kidney:0.51 pituitary:- thyroid/parathyroid:0.79 adrenal gland:2.21 pancreas:- breast:3.28 salivary:-

Gene Information

IDs

Refseq ID NM_005586
Gene ID 4188
Unigene ID Hs.520119
Probe set ID 205375_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000112559
GTEx ID ENSG00000112559

Orthologous Gene

Mouse[2]  NM_001109973, NM_010783
Rat[1]  NM_001109301, NM_010783

Chromosomal Region

6p21.1  [41,604,620  -  41,621,984]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8797820
9250874
9799236
11238923
12107410
12477932
14530267
14574404
15207726
15489334
16189514
16713569
17289077
19060904
19447967
19850743
21664411
22632162
23088713

Gene Ontology  (GO ID)

Biological Process

GO:0007257  activation of JUN kinase activity
GO:0042994  cytoplasmic sequestering of transcription factor
GO:0009950  dorsal/ventral axis specification
GO:0009790  embryonic development
GO:0048704  embryonic skeletal system morphogenesis
GO:0043392  negative regulation of DNA binding
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0060707  trophoblast giant cell differentiation

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0005515  protein binding
GO:0008134  transcription factor binding