Mdm4 p53 binding protein homolog (mouse)

Synonym

Mdm4 protein, Double minute 4 protein, Mdm2-like p53-binding protein, MDMX, DKFZp781B1423, MGC132766, MDM4, Mdmx protein, p53-binding protein Mdm4

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:39.10

cerebellum:37.80

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:112.30

retina:-

eye:52.90

artery/aorta:89.90

vein:-

lymphnode:151.70

peripheral blood:36.40

spleen:189.10

thymus:708.60

bone marrow:98.40

adipose:40.30

bone:38.40

skin:110.40

GeneChip

cerebrum:2.89

cerebellum:2.94

brain stem:2.95

corpus callosum/glia:3.05

pineal gland:-

peripheral nerve:2.77

spine:2.92

retina:-

eye:-

artery/aorta:2.83

vein:2.88

lymphnode:2.85

peripheral blood:-

spleen:3.01

thymus:6.51

bone marrow:3.05

adipose:2.94

bone:-

skin:2.81

CAGE

cerebrum:3.91

cerebellum:-

brain stem:4.07

corpus callosum/glia:4.35

pineal gland:4.24

peripheral nerve:-

spine:4.16

retina:-

eye:-

artery/aorta:4.01

vein:4.47

lymphnode:4.18

peripheral blood:-

spleen:3.75

thymus:5.07

bone marrow:-

adipose:3.80

bone:-

skin:-

RNA-seq

cerebrum:2.33

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.38

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.74

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:63.80

placenta:43.70

prostate:67.60

ovary:37.30

testis:73.50

heart:38.30

muscle:20.10

esophagus:-

stomach:127.50

intestine:97.20

colon:135.70

liver/hepato:31.70

lung:58.70

bladder:-

kidney:41.60

pituitary:116

thyroid/parathyroid:-

adrenal gland:101.60

pancreas:35.60

breast:148.70

salivary:328.40

GeneChip

uterus:3.06

placenta:3.10

prostate:2.92

ovary:2.88

testis:2.77

heart:2.95

muscle:2.86

esophagus:2.80

stomach:2.81

intestine:2.99

colon:3.15

liver/hepato:2.65

lung:2.90

bladder:-

kidney:2.89

pituitary:2.83

thyroid/parathyroid:2.75

adrenal gland:2.63

pancreas:2.77

breast:2.82

salivary:2.87

CAGE

uterus:3.90

placenta:3.54

prostate:3.60

ovary:3.87

testis:3.77

heart:3.56

muscle:3.69

esophagus:3.28

stomach:-

intestine:3.43

colon:3.74

liver/hepato:2.79

lung:3.64

bladder:3.99

kidney:3.24

pituitary:4.20

thyroid/parathyroid:3.32

adrenal gland:-

pancreas:4.22

breast:3.66

salivary:3.67

RNA-seq

uterus:-

placenta:-

prostate:1.01

ovary:3.17

testis:1.82

heart:0.80

muscle:1.24

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.00

lung:0.00

bladder:-

kidney:0.51

pituitary:-

thyroid/parathyroid:1.67

adrenal gland:2.53

pancreas:-

breast:2.44

salivary:-

IDs

Refseq ID	NM_002393
Gene ID	4194
Unigene ID	Hs.497492
Probe set ID	205655_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000198625
GTEx ID	ENSG00000198625

Orthologous Gene

Mouse[1]	NM_008575
Rat[1]	NM_001012026

Chromosomal Region

1q32.1 [204,485,511 - 204,542,871]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR016495

p53 negative regulator Mdm2/Mdm4

GO:0008283	cell proliferation
GO:0071456	cellular response to hypoxia
GO:0030330	DNA damage response, signal transduction by p53 class mediator
GO:0045023	G0 to G1 transition
GO:0043066	negative regulation of apoptosis
GO:0071157	negative regulation of cell cycle arrest
GO:0008285	negative regulation of cell proliferation
GO:0042177	negative regulation of protein catabolic process
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0008284	positive regulation of cell proliferation
GO:0006461	protein complex assembly
GO:0050821	protein stabilization

GO:0019899	enzyme binding
GO:0005515	protein binding
GO:0008270	zinc ion binding

Mdm4 p53 binding protein homolog (mouse)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function