RAB8A, member RAS oncogene family

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Synonym

Ras-related protein Rab-8A, RAB8A, member RAS oncogene family, Oncogene c-mel, MEL, RAB8A, RAB8

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:7.23 cerebellum:7.18 brain stem:7.25 corpus callosum/glia:7.63 pineal gland:- peripheral nerve:7.98 spine:7.77 retina:- eye:- artery/aorta:8.12 vein:7.72 lymphnode:8.49 peripheral blood:- spleen:8.58 thymus:8.58 bone marrow:8.30 adipose:7.90 bone:- skin:7.93
CAGE cerebrum:3.71 cerebellum:- brain stem:3.77 corpus callosum/glia:4.09 pineal gland:3.64 peripheral nerve:- spine:4.06 retina:- eye:- artery/aorta:4.00 vein:4.19 lymphnode:4.49 peripheral blood:- spleen:4.87 thymus:4.47 bone marrow:- adipose:4.34 bone:- skin:-
RNA-seq cerebrum:3.18 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.84 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.80 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.88 placenta:7.94 prostate:8.39 ovary:8.23 testis:7.94 heart:7.11 muscle:6.21 esophagus:8.38 stomach:7.98 intestine:7.90 colon:8.51 liver/hepato:8.59 lung:8.62 bladder:- kidney:8.11 pituitary:7.54 thyroid/parathyroid:7.89 adrenal gland:7.90 pancreas:7.77 breast:8.19 salivary:8.24
CAGE uterus:4.06 placenta:4.48 prostate:4.01 ovary:4.29 testis:4.08 heart:3.41 muscle:2.84 esophagus:4.06 stomach:- intestine:5.12 colon:4.16     liver/hepato:5.02    lung:4.31 bladder:4.03 kidney:4.32 pituitary:3.92 thyroid/parathyroid:4.01 adrenal gland:- pancreas:4.26 breast:3.69 salivary:4.56
RNA-seq uterus:- placenta:- prostate:4.67 ovary:4.89 testis:4.45 heart:2.55 muscle:2.32 esophagus:- stomach:- intestine:- colon:3.87     liver/hepato:5.00        lung:4.40    bladder:- kidney:4.37 pituitary:- thyroid/parathyroid:4.14 adrenal gland:4.77 pancreas:- breast:4.07 salivary:-

Gene Information

IDs

Refseq ID NM_005370
Gene ID 4218
Unigene ID -
Probe set ID 208819_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000167461
GTEx ID ENSG00000167461

Orthologous Gene

Mouse[1]  NM_023126
Rat [0]  

Chromosomal Region

19p13.12  [16,222,490  -  16,244,443]

Gene Family (Interpro ID)

IPR002041  Ran GTPase
IPR013753  Ras
IPR001806  Ras GTPase
IPR020849  Ras small GTPase
IPR003579  Ras small GTPase, Rab type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR003578  Small GTPase, Rho type

Link to Pubmed  (Pubmed ID)

123217
1886711
2564840
8294494
8375503
8408203
8643544
9226381
9677305
9918381
10512627
11137014
11773082
12176990
12221131
12477932
12578829
12590134
12639940
15207266
15489334
15837803
16169070
16473576
16541104
16902405
17050734
17081983
17332756
17353931
17507647
17574030
17597763
17646400
18714005
18724065
18772192
18976975
19056867
19304576
19322201
19641326
19864458
20085643
20161783
20237496
20308558
20360068
20424170
20631154
20634958
20937822
21139048
21596566
21906983
21963094
22159412
22178446
22219378
22433857
22445341
22790198
22854040
22939629
23000965
23014846
23125841
23140275
23175844
23246001
23303251
23357852
23435566
23606746
24072714
24250222
24255178
24332808
24515439
24583282
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0007409  axonogenesis
GO:0042384  cilium assembly
GO:0000086  G2/M transition of mitotic cell cycle
GO:0048210  Golgi vesicle fusion to target membrane
GO:0006184  GTP catabolic process
GO:0016044  membrane organization
GO:0000278  mitotic cell cycle
GO:0015031  protein transport
GO:0048169  regulation of long-term neuronal synaptic plasticity
GO:0051223  regulation of protein transport
GO:0007264  small GTPase mediated signal transduction
GO:0006904  vesicle docking during exocytosis

Cellular Component

GO:0043025  cell soma
GO:0005929  cilium
GO:0030659  cytoplasmic vesicle membrane
GO:0030425  dendrite
GO:0000139  Golgi membrane
GO:0005932  microtubule basal body
GO:0031513  nonmotile primary cilium
GO:0048471  perinuclear region of cytoplasm
GO:0045335  phagocytic vesicle
GO:0030670  phagocytic vesicle membrane
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0055037  recycling endosome

Molecular Function

GO:0019003  GDP binding
GO:0005525  GTP binding
GO:0003924  GTPase activity
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0017137  Rab GTPase binding