activating transcription factor 4 (tax-responsive enhancer element B67)

Synonym

TXREB, CREB-2, DNA-binding protein TAXREB67, Cyclic AMP-dependent transcription factor ATF-4, Cyclic AMP response element-binding protein 2, TAXREB67, Activating transcription factor 4, ATF4, CREB2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:203.80

cerebellum:163.70

brain stem:-

corpus callosum/glia:320.80

pineal gland:-

peripheral nerve:245.40

spine:673.80

retina:237.30

eye:346.70

artery/aorta:869.30

vein:199.90

lymphnode:303.30

peripheral blood:200.40

spleen:189.10

thymus:141.70

bone marrow:669.10

adipose:645.30

bone:191.90

skin:259.20

GeneChip

cerebrum:9.23

cerebellum:9.43

brain stem:9.39

corpus callosum/glia:9.47

pineal gland:-

peripheral nerve:9.59

spine:9.41

retina:-

eye:-

artery/aorta:10.42

vein:10.50

lymphnode:9.78

peripheral blood:-

spleen:9.56

thymus:9.60

bone marrow:9.57

adipose:10.19

bone:-

skin:9.97

CAGE

cerebrum:5.12

cerebellum:-

brain stem:5.24

corpus callosum/glia:4.89

pineal gland:4.91

peripheral nerve:-

spine:6.01

retina:-

eye:-

artery/aorta:6.05

vein:5.31

lymphnode:5.19

peripheral blood:-

spleen:5.05

thymus:4.46

bone marrow:-

adipose:5.51

bone:-

skin:-

RNA-seq

cerebrum:6.26

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:7.72

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:6.94

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:337.20

placenta:448.10

prostate:315.40

ovary:111.80

testis:103.80

heart:89.40

muscle:904.10

esophagus:-

stomach:169.90

intestine:291.60

colon:678.40

liver/hepato:179.40

lung:278.60

bladder:251.20

kidney:62.40

pituitary:-

thyroid/parathyroid:163.70

adrenal gland:355.50

pancreas:346.80

breast:343.80

salivary:328.40

GeneChip

uterus:9.97

placenta:9.89

prostate:10.12

ovary:9.75

testis:9.13

heart:9.52

muscle:10.37

esophagus:9.85

stomach:10.06

intestine:10.08

colon:9.73

liver/hepato:9.52

lung:10.22

bladder:-

kidney:9.14

pituitary:9.42

thyroid/parathyroid:9.48

adrenal gland:10.08

pancreas:9.99

breast:9.98

salivary:10.46

CAGE

uterus:5.37

placenta:5.43

prostate:5.78

ovary:5.49

testis:4.95

heart:5.33

muscle:6.08

esophagus:5.78

stomach:-

intestine:5.13

colon:5.79

liver/hepato:5.84

lung:5.42

bladder:6.35

kidney:5.02

pituitary:5.03

thyroid/parathyroid:5.57

adrenal gland:-

pancreas:6.24

breast:6.54

salivary:6.05

RNA-seq

uterus:-

placenta:-

prostate:8.71

ovary:7.75

testis:6.95

heart:6.48

muscle:7.93

esophagus:-

stomach:-

intestine:-

colon:8.53

liver/hepato:6.72

lung:7.73

bladder:-

kidney:6.67

pituitary:-

thyroid/parathyroid:7.12

adrenal gland:7.36

pancreas:-

breast:7.06

salivary:-

IDs

Refseq ID	NM_182810
Gene ID	468
Unigene ID	Hs.496487
Probe set ID	200779_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000128272
GTEx ID	ENSG00000128272

Orthologous Gene

Mouse[1]	NM_009716
Rat [0]

Chromosomal Region

22q13.1 [39,915,700 - 39,918,691]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR004827

Basic-leucine zipper (bZIP) transcription factor

Gene Ontology (GO ID)

Biological Process

GO:0006987	activation of signaling protein activity involved in unfolded protein response
GO:0070059	apoptosis in response to endoplasmic reticulum stress
GO:0006520	cellular amino acid metabolic process
GO:0044267	cellular protein metabolic process
GO:0030968	endoplasmic reticulum unfolded protein response
GO:0007214	gamma-aminobutyric acid signaling pathway
GO:0006094	gluconeogenesis
GO:0043267	negative regulation of potassium ion transport
GO:0043525	positive regulation of neuron apoptosis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006355	regulation of transcription, DNA-dependent
GO:0034976	response to endoplasmic reticulum stress
GO:0006366	transcription from RNA polymerase II promoter

Cellular Component

GO:0005737	cytoplasm
GO:0032590	dendrite membrane
GO:0005815	microtubule organizing center
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0003677	DNA binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity

activating transcription factor 4 (tax-responsive enhancer element B67)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function