ATP citrate lyase

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Synonym

Citrate cleavage enzyme, CLATP, ATP citrate lyase, ATPCL, ACL, ATP-citrate (pro-S-)-lyase, ATP-citrate synthase, ACLY

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:183.70

cerebellum:176.30

brain stem:-

corpus callosum/glia:29.20

pineal gland:593.40

peripheral nerve:-

spine:449.20

retina:-

eye:29.40

artery/aorta:119.90

vein:266.60

lymphnode:171.90

peripheral blood:18.20

spleen:37.80

thymus:154.60

bone marrow:19.70

adipose:80.70

bone:76.80

skin:57.60

GeneChip

cerebrum:7.99

cerebellum:7.78

brain stem:8.52

corpus callosum/glia:7.80

pineal gland:-

peripheral nerve:9.57

spine:8.52

retina:-

eye:-

artery/aorta:8.07

vein:8.21

lymphnode:8.23

peripheral blood:-

spleen:8.51

thymus:8.33

bone marrow:7.92

adipose:8.92

bone:-

skin:7.86

CAGE

cerebrum:3.36

cerebellum:-

brain stem:3.75

corpus callosum/glia:3.50

pineal gland:5.30

peripheral nerve:-

spine:3.61

retina:-

eye:-

artery/aorta:3.61

vein:3.49

lymphnode:3.55

peripheral blood:-

spleen:3.46

thymus:3.57

bone marrow:-

adipose:3.50

bone:-

skin:-

RNA-seq

cerebrum:3.68

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.14

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.72

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:82

placenta:65.60

prostate:146.40

ovary:74.50

testis:134.10

heart:76.60

muscle:-

esophagus:-

stomach:21.20

intestine:-

colon:84.80

liver/hepato:42.20

lung:156.40

bladder:125.60

kidney:31.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:101.60

pancreas:62.20

breast:83.60

salivary:-

GeneChip

uterus:8.13

placenta:8.48

prostate:9.41

ovary:8.19

testis:8.14

heart:7.57

muscle:6.40

esophagus:7.53

stomach:8.15

intestine:8.14

colon:7.99

liver/hepato:7.74

lung:8.28

bladder:-

kidney:8.49

pituitary:7.92

thyroid/parathyroid:7.99

adrenal gland:8.22

pancreas:8.04

breast:8.67

salivary:7.82

CAGE

uterus:3.05

placenta:3.49

prostate:3.46

ovary:3.28

testis:3.46

heart:3.24

muscle:2.57

esophagus:3.40

stomach:-

intestine:3.71

colon:3.52

liver/hepato:3.28

lung:3.53

bladder:3.32

kidney:3.92

pituitary:2.79

thyroid/parathyroid:3.17

adrenal gland:-

pancreas:3.67

breast:3.81

salivary:3.22

RNA-seq

uterus:-

placenta:-

prostate:3.35

ovary:4.07

testis:4.83

heart:2.14

muscle:2.25

esophagus:-

stomach:-

intestine:-

colon:3.53

liver/hepato:3.30

lung:1.96

bladder:-

kidney:4.36

pituitary:-

thyroid/parathyroid:3.73

adrenal gland:3.55

pancreas:-

breast:4.50

salivary:-

IDs

Refseq ID	NM_198830
Gene ID	47
Unigene ID	Hs.387567
Probe set ID	201128_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000131473
GTEx ID	ENSG00000131473

Orthologous Gene

Mouse[3]	NM_001199296, NM_134037
Rat[6]	NM_001111095, NM_016987

Chromosomal Region

17q21.2 [40,023,161 - 40,075,272]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR003781	CoA-binding
IPR016040	NAD(P)-binding domain

GO:0006200	ATP catabolic process
GO:0044262	cellular carbohydrate metabolic process
GO:0044255	cellular lipid metabolic process
GO:0006101	citrate metabolic process
GO:0015936	coenzyme A metabolic process
GO:0006112	energy reserve metabolic process
GO:0031325	positive regulation of cellular metabolic process
GO:0019432	triglyceride biosynthetic process

GO:0009346	citrate lyase complex
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005739	mitochondrion
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0005886	plasma membrane

GO:0005524	ATP binding
GO:0003878	ATP citrate synthase activity
GO:0048037	cofactor binding
GO:0046872	metal ion binding
GO:0004775	succinate-CoA ligase (ADP-forming) activity

ATP citrate lyase

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function