purinergic receptor P2X, ligand-gated ion channel, 5

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Synonym

P2X5R, P2RX5, P2X purinoceptor 5, P2X5, MGC47755

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:19 cerebellum:12.60 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:- vein:- lymphnode:70.80 peripheral blood:91.10 spleen:226.90 thymus:12.90 bone marrow:19.70 adipose:- bone:- skin:9.60
GeneChip cerebrum:6.14 cerebellum:5.99 brain stem:5.89 corpus callosum/glia:5.25 pineal gland:- peripheral nerve:6.20 spine:5.66 retina:- eye:- artery/aorta:5.41 vein:5.30 lymphnode:8.49 peripheral blood:- spleen:9.71 thymus:7.43 bone marrow:7.71 adipose:6.15 bone:- skin:5.40
CAGE cerebrum:0.96 cerebellum:- brain stem:0.70 corpus callosum/glia:0.29 pineal gland:1.00 peripheral nerve:- spine:0.52 retina:- eye:- artery/aorta:0.34 vein:2.75 lymphnode:2.88 peripheral blood:- spleen:3.22 thymus:2.41 bone marrow:- adipose:0.14 bone:- skin:-
RNA-seq cerebrum:0.47 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.53 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.05 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:- salivary:-
GeneChip uterus:4.92 placenta:5.05 prostate:5.06 ovary:5.12 testis:5.44 heart:5.67 muscle:6.60 esophagus:5.33 stomach:6.13 intestine:6.10 colon:6.29 liver/hepato:5.44 lung:5.73 bladder:- kidney:5.13 pituitary:5.45 thyroid/parathyroid:5.37 adrenal gland:5.30 pancreas:5.62 breast:5.20 salivary:5.44
CAGE uterus:0.16 placenta:0 prostate:0.27 ovary:0.20 testis:0.10 heart:0.87 muscle:2.14 esophagus:1.08 stomach:- intestine:0.87 colon:1.07     liver/hepato:0    lung:0.58 bladder:0.95 kidney:0.44 pituitary:0.83 thyroid/parathyroid:0.12 adrenal gland:- pancreas:0 breast:0 salivary:0.83
RNA-seq uterus:- placenta:- prostate:0.28 ovary:0.06 testis:0.07 heart:0.50 muscle:0.47 esophagus:- stomach:- intestine:- colon:0.17     liver/hepato:0.31        lung:0.76    bladder:- kidney:0.35 pituitary:- thyroid/parathyroid:0.00 adrenal gland:1.07 pancreas:- breast:0.05 salivary:-

Gene Information

IDs

Refseq ID NM_175080
Gene ID 5026
Unigene ID Hs.408615
Probe set ID 210448_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000083454
GTEx ID ENSG00000083454

Orthologous Gene

Mouse[1]  NM_033321
Rat [0]  

Chromosomal Region

17p13.2  [3,575,748  -  3,599,698]

Gene Family (Interpro ID)

IPR001429  P2X purinoreceptor
IPR003048  P2X5 purinoceptor

Link to Pubmed  (Pubmed ID)

8619474
9110174
9414125
10673275
12270951
12477932
12665801
12787128
12880424
14702039
16322791
16967306
17001079
17207965
17895406
18719914
18976975
19074734
20223879
20962269
21092862
21963094

Gene Ontology  (GO ID)

Biological Process

GO:0006812  cation transport
GO:0007399  nervous system development
GO:0010524  positive regulation of calcium ion transport into cytosol
GO:0050850  positive regulation of calcium-mediated signaling
GO:0007165  signal transduction
GO:0006810  transport

Cellular Component

GO:0005887  integral to plasma membrane
GO:0016020  membrane

Molecular Function

GO:0005524  ATP binding
GO:0004931  ATP-gated cation channel activity
GO:0005216  ion channel activity
GO:0001614  purinergic nucleotide receptor activity
GO:0004888  transmembrane receptor activity