sclerosteosis

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Synonym

sclerosteosis, SOST, UNQ2976/PRO7455/PRO7476, Sclerostin precursor, VBCH

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:30

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:25.60

skin:-

GeneChip

nodata

CAGE

cerebrum:0.09

cerebellum:-

brain stem:0.03

corpus callosum/glia:0

pineal gland:0

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:5.06

vein:1.80

lymphnode:0

peripheral blood:-

spleen:0

thymus:0.06

bone marrow:-

adipose:0.14

bone:-

skin:-

RNA-seq

cerebrum:0.07

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.22

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:93.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

nodata

CAGE

uterus:0.07

placenta:0.08

prostate:0.08

ovary:0.07

testis:0

heart:0.64

muscle:0

esophagus:0.09

stomach:-

intestine:0

colon:0.04

liver/hepato:0

lung:0.67

bladder:0

kidney:1.19

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.06

ovary:0

testis:0.06

heart:0.17

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0

liver/hepato:0

lung:0.31

bladder:-

kidney:0.96

pituitary:-

thyroid/parathyroid:0

adrenal gland:0

pancreas:-

breast:0

salivary:-

IDs

Refseq ID	NM_025237
Gene ID	50964
Unigene ID	Hs.349204
Probe set ID	-
Ensembl ID	ENSG00000167941
GTEx ID	ENSG00000167941

Orthologous Gene

Mouse[2]	NM_024449
Rat[1]	NM_030584

Chromosomal Region

17q21.31 [41,831,103 - 41,836,156]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR006207

Cystine knot, C-terminal

GO:0071374	cellular response to parathyroid hormone stimulus
GO:0030514	negative regulation of BMP signaling pathway
GO:0030279	negative regulation of ossification
GO:0031333	negative regulation of protein complex assembly
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0001503	ossification
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0009612	response to mechanical stimulus
GO:0016055	Wnt receptor signaling pathway

GO:0031012	extracellular matrix
GO:0005615	extracellular space
GO:0005794	Golgi apparatus
GO:0005578	proteinaceous extracellular matrix

GO:0008201	heparin binding
GO:0005515	protein binding
GO:0008134	transcription factor binding

sclerosteosis

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function