prohibitin

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Synonym

Prohibitin, PHB, prohibitin

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:100.70

cerebellum:176.30

brain stem:-

corpus callosum/glia:87.50

pineal gland:296.70

peripheral nerve:-

spine:224.60

retina:-

eye:164.60

artery/aorta:239.80

vein:199.90

lymphnode:101.10

peripheral blood:109.30

spleen:94.50

thymus:90.20

bone marrow:39.40

adipose:161.30

bone:127.90

skin:91.20

GeneChip

cerebrum:6.88

cerebellum:6.25

brain stem:7.10

corpus callosum/glia:6.69

pineal gland:-

peripheral nerve:7.26

spine:6.61

retina:-

eye:-

artery/aorta:6.97

vein:6.83

lymphnode:6.91

peripheral blood:-

spleen:6.49

thymus:7.18

bone marrow:6.55

adipose:7.15

bone:-

skin:7.24

CAGE

cerebrum:2.26

cerebellum:-

brain stem:2.50

corpus callosum/glia:2.54

pineal gland:1.86

peripheral nerve:-

spine:2.27

retina:-

eye:-

artery/aorta:2.41

vein:1.86

lymphnode:2.11

peripheral blood:-

spleen:2.41

thymus:2.31

bone marrow:-

adipose:2.57

bone:-

skin:-

RNA-seq

cerebrum:4.05

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.58

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.59

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:173.20

placenta:80.10

prostate:214

ovary:186.30

testis:138.40

heart:153.30

muscle:100.50

esophagus:342.80

stomach:339.90

intestine:324

colon:245.90

liver/hepato:116.10

lung:122.20

bladder:-

kidney:207.90

pituitary:-

thyroid/parathyroid:982.50

adrenal gland:558.70

pancreas:160

breast:139.40

salivary:-

GeneChip

uterus:7.30

placenta:6.61

prostate:7.60

ovary:7.71

testis:6.56

heart:7.56

muscle:7.60

esophagus:7.52

stomach:6.95

intestine:7.51

colon:7.96

liver/hepato:6.72

lung:7.05

bladder:-

kidney:7.97

pituitary:6.27

thyroid/parathyroid:7.17

adrenal gland:6.97

pancreas:7.03

breast:7.24

salivary:8.78

CAGE

uterus:2.32

placenta:2.44

prostate:2.57

ovary:2.74

testis:2.28

heart:2.73

muscle:2.78

esophagus:2.70

stomach:-

intestine:2.76

colon:2.72

liver/hepato:3.09

lung:2.19

bladder:2.30

kidney:3.17

pituitary:2.19

thyroid/parathyroid:2.91

adrenal gland:-

pancreas:2.34

breast:2.02

salivary:3.19

RNA-seq

uterus:-

placenta:-

prostate:5.21

ovary:5.12

testis:4.84

heart:4.52

muscle:4.44

esophagus:-

stomach:-

intestine:-

colon:5.20

liver/hepato:4.96

lung:4.11

bladder:-

kidney:5.87

pituitary:-

thyroid/parathyroid:5.43

adrenal gland:5.14

pancreas:-

breast:5.04

salivary:-

IDs

Refseq ID	NM_002634
Gene ID	5245
Unigene ID	Hs.514303
Probe set ID	200658_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000167085
GTEx ID	ENSG00000167085

Orthologous Gene

Mouse[2]	NM_008831
Rat[2]	NM_008831

Chromosomal Region

17q21.33 [47,481,414 - 47,492,246]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001107	Band 7 protein
IPR000163	Prohibitin

Gene Ontology (GO ID)

Biological Process

GO:0071354	cellular response to interleukin-6
GO:0006260	DNA replication
GO:0016575	histone deacetylation
GO:0060766	negative regulation of androgen receptor signaling pathway
GO:0030308	negative regulation of cell growth
GO:0008285	negative regulation of cell proliferation
GO:0010944	negative regulation of transcription by competitive promoter binding
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0050847	progesterone receptor signaling pathway
GO:0042981	regulation of apoptosis
GO:0006355	regulation of transcription, DNA-dependent
GO:0007165	signal transduction

Cellular Component

GO:0005737	cytoplasm
GO:0005887	integral to plasma membrane
GO:0005743	mitochondrial inner membrane
GO:0005739	mitochondrion
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0044212	DNA regulatory region binding
GO:0042826	histone deacetylase binding
GO:0005515	protein binding

prohibitin

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function