ubiquitin associated and SH3 domain containing, A

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Synonym

TULA, T-cell ubiquitin ligand, STS2, CLIP4, Cbl-interacting protein 4, STS-2, ubiquitin associated and SH3 domain containing, A, Suppressor of T-cell receptor signaling 2, UBASH3A

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:2.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:50.60 peripheral blood:54.70 spleen:94.50 thymus:116 bone marrow:39.40 adipose:40.30 bone:38.40 skin:-
GeneChip nodata
CAGE cerebrum:0.08 cerebellum:- brain stem:0.39 corpus callosum/glia:0.29 pineal gland:0.14 peripheral nerve:- spine:0.30 retina:- eye:- artery/aorta:0.87 vein:3.37 lymphnode:3.33 peripheral blood:- spleen:2.25 thymus:4.37 bone marrow:- adipose:0.36 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.24 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:33.80 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:32.40 colon:17     liver/hepato:21.10        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:0.82 placenta:0.48 prostate:0.94 ovary:0.76 testis:0.34 heart:0.56 muscle:0.17 esophagus:1.08 stomach:- intestine:1.89 colon:1.64     liver/hepato:0.36    lung:2.25 bladder:1.52 kidney:0.62 pituitary:0 thyroid/parathyroid:0.53 adrenal gland:- pancreas:0 breast:0.90 salivary:1.75
RNA-seq uterus:- placenta:- prostate:0.07 ovary:0.10 testis:0.09 heart:0.00 muscle:0 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.65    bladder:- kidney:0.13 pituitary:- thyroid/parathyroid:0.00 adrenal gland:1.57 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_001001895
Gene ID 53347
Unigene ID Hs.473912
Probe set ID -
Ensembl ID ENSG00000160185
GTEx ID ENSG00000160185

Orthologous Gene

Mouse[1]  NM_177823
Rat[1]  NM_001107620

Chromosomal Region

21q22.3  [43,824,008  -  43,867,791]

Gene Family (Interpro ID)

IPR000449  Ubiquitin-associated/translation elongation factor EF1B, N-terminal
IPR015940  Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote

Link to Pubmed  (Pubmed ID)

11281453
12477932
14968112
15107835
15159412
15489334
16344560
16429130
16780588
17382318
17588522
17599067
17709377
17880946
18006034
18189269
18344182
18840781
18854154
19073967
19380743
19430480
19585081
20410501
20453842
20494980
20647273
21383967
21829393
22505724
22776074
23565265

Gene Ontology  (GO ID)

Biological Process

GO:0050860  negative regulation of T cell receptor signaling pathway
GO:0001817  regulation of cytokine production
GO:0016070  RNA metabolic process

Cellular Component

GO:0005829  cytosol
GO:0005634  nucleus

Molecular Function

GO:0003824  catalytic activity