DEAD (Asp-Glu-Ala-Asp) box polypeptide 4

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Synonym

DEAD box protein 4, MGC111074, Probable ATP-dependent RNA helicase DDX4, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4, DDX4, VASA homolog, DEAD (Asp-Glu-Ala-Asp) box polypeptide 4, VASA

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.16 cerebellum:3.16 brain stem:3.23 corpus callosum/glia:3.08 pineal gland:- peripheral nerve:3.02 spine:3.11 retina:- eye:- artery/aorta:3.18 vein:3.33 lymphnode:3.07 peripheral blood:- spleen:2.98 thymus:2.87 bone marrow:3.17 adipose:3.12 bone:- skin:3.24
CAGE cerebrum:0.00 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:579.70 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.04 placenta:3.20 prostate:2.92 ovary:3.24 testis:8.75 heart:3.16 muscle:3.26 esophagus:3.08 stomach:3.02 intestine:3.20 colon:3.19 liver/hepato:3.06 lung:3.26 bladder:- kidney:3.01 pituitary:3.02 thyroid/parathyroid:3.01 adrenal gland:2.93 pancreas:3.11 breast:3 salivary:2.99
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:4.40 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:2.82 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0.00 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_001142549
Gene ID 54514
Unigene ID Hs.223581
Probe set ID 221630_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000152670
GTEx ID ENSG00000152670

Orthologous Gene

Mouse[2]  NM_001145885, NM_010029
Rat[1]  NM_001077647, NM_010029

Chromosomal Region

5q11.2  [55,033,845  -  55,112,985]

Gene Family (Interpro ID)

IPR014001  DEAD-like helicase, N-terminal
IPR014021  Helicase, superfamily 1/2, ATP-binding domain

Link to Pubmed  (Pubmed ID)

10920202
11850529
12477932
14648869
14702039
14736746
15489334
16344560
17486274
17868192
18534994
18729074
18805576
19629140
19937754
20561531
21145461
21987572
22162380
22288104
23315064

Gene Ontology  (GO ID)

Biological Process

GO:0007141  male meiosis I
GO:0007275  multicellular organismal development
GO:0032880  regulation of protein localization
GO:0030317  sperm motility
GO:0007283  spermatogenesis

Cellular Component

GO:0033391  chromatoid body
GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm

Molecular Function

GO:0005524  ATP binding
GO:0008026  ATP-dependent helicase activity
GO:0003676  nucleic acid binding