UDP glucuronosyltransferase 1 family, polypeptide A8

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Synonym

UGT-1H, UGT1A8, UGT1H, UGT1*8, UGT1-08, UDP-glucuronosyltransferase 1A8, UDP-glucuronosyltransferase 1-8 precursor, UGT1.8

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:3.21 cerebellum:3.13 brain stem:3.28 corpus callosum/glia:3.11 pineal gland:- peripheral nerve:3.09 spine:3.09 retina:- eye:- artery/aorta:3.25 vein:3.17 lymphnode:3.11 peripheral blood:- spleen:3.12 thymus:2.90 bone marrow:3.19 adipose:3.27 bone:- skin:3.63
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0.19 peripheral blood:- spleen:0 thymus:0.12 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:2.95 placenta:3.23 prostate:3.06 ovary:2.89 testis:2.91 heart:3.12 muscle:3.37 esophagus:5.16 stomach:3.35 intestine:3.49 colon:5.29 liver/hepato:5.27 lung:2.97 bladder:- kidney:6.75 pituitary:3.02 thyroid/parathyroid:2.90 adrenal gland:3.13 pancreas:3.15 breast:3.13 salivary:3.14
CAGE uterus:0 placenta:0 prostate:0.44 ovary:0 testis:0 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0.15     liver/hepato:0    lung:0 bladder:0.53 kidney:0.67 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:1.88 ovary:0 testis:0.00 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0.35     liver/hepato:0.18        lung:0.00    bladder:- kidney:2.21 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0 pancreas:- breast:0.02 salivary:-

Gene Information

IDs

Refseq ID NM_019076
Gene ID 54576
Unigene ID -
Probe set ID 221305_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000242366
GTEx ID ENSG00000242366

Orthologous Gene

Mouse[9]  NM_201642, NM_201641, NM_201644
Rat[9]  NM_201642, NM_201641, NM_201644

Chromosomal Region

2q37.1  [234,526,291  -  234,681,956]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1339448
8467709
9295054
9535849
9647757
9705221
10497143
10836148
11179460
11434514
11465080
11901093
12042666
12433820
12639971
12695355
12847094
12920167
14672974
15057901
15247627
15319294
16397224
17179145
17339869
17603215
18052087
18454993
18568343
18695635
18946804
19225446
19244109
19414484
19419973
19898482
19913121
19996319
20147615
20297805
20379614
20453000
20565459
20628086
20639394
20732626
20972438
21646302
21886157
22085899
22367021
22511988
22558097
23281178
23371916
23642732
23682072
23700788
23721685
24097068
24163127

Gene Ontology  (GO ID)

Biological Process

GO:0009804  coumarin metabolic process
GO:0017144  drug metabolic process
GO:0006631  fatty acid metabolic process
GO:0051552  flavone metabolic process
GO:0043086  negative regulation of catalytic activity
GO:0031324  negative regulation of cellular metabolic process
GO:0045922  negative regulation of fatty acid metabolic process
GO:0045939  negative regulation of steroid metabolic process
GO:0042573  retinoic acid metabolic process
GO:0008202  steroid metabolic process

Cellular Component

GO:0005789  endoplasmic reticulum membrane
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle

Molecular Function

GO:0008144  drug binding
GO:0019899  enzyme binding
GO:0004857  enzyme inhibitor activity
GO:0005504  fatty acid binding
GO:0015020  glucuronosyltransferase activity
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0001972  retinoic acid binding
GO:0005496  steroid binding