Abelson helper integration site 1

 jump to detail

Synonym

dJ71N10.1, FLJ14023, Abelson helper integration site, AHI1, Jouberin, Abelson helper integration site 1 protein homolog, Abelson helper integration site 1, DKFZp686J1653, FLJ20069, JBTS3, AHI-1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:45 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:296.70 peripheral nerve:30.70 spine:224.60 retina:237.30 eye:88.20 artery/aorta:60 vein:- lymphnode:10.10 peripheral blood:54.70 spleen:18.90 thymus:25.80 bone marrow:- adipose:40.30 bone:38.40 skin:24
GeneChip cerebrum:5.02 cerebellum:5.34 brain stem:4.93 corpus callosum/glia:4.53 pineal gland:- peripheral nerve:4.62 spine:4.72 retina:- eye:- artery/aorta:4.73 vein:4.70 lymphnode:4.44 peripheral blood:- spleen:4.25 thymus:4.50 bone marrow:4.33 adipose:4.59 bone:- skin:4.60
CAGE cerebrum:4.33 cerebellum:- brain stem:4.15 corpus callosum/glia:3.09 pineal gland:5.49 peripheral nerve:- spine:4.61 retina:- eye:- artery/aorta:2.99 vein:2.93 lymphnode:2.36 peripheral blood:- spleen:2.62 thymus:3.32 bone marrow:- adipose:3.12 bone:- skin:-
RNA-seq cerebrum:0.13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:18.20 prostate:169 ovary:74.50 testis:151.40 heart:12.80 muscle:60.30 esophagus:- stomach:106.20 intestine:- colon:25.40     liver/hepato:158.30        lung:53.80    bladder:- kidney:124.80 pituitary:463.90 thyroid/parathyroid:163.70 adrenal gland:- pancreas:133.40 breast:18.60 salivary:-
GeneChip uterus:4.75 placenta:4.32 prostate:4.90 ovary:4.55 testis:5.86 heart:4.45 muscle:4.46 esophagus:4.57 stomach:4.66 intestine:4.48 colon:4.43 liver/hepato:4.48 lung:4.44 bladder:- kidney:4.46 pituitary:5.67 thyroid/parathyroid:4.38 adrenal gland:4.95 pancreas:4.56 breast:4.44 salivary:4.62
CAGE uterus:3.80 placenta:2.79 prostate:3.69 ovary:3.80 testis:3.86 heart:3.45 muscle:3.12 esophagus:3.06 stomach:- intestine:2.88 colon:3.18     liver/hepato:2.70    lung:3.53 bladder:3.71 kidney:3.26 pituitary:5.44 thyroid/parathyroid:3.02 adrenal gland:- pancreas:2.86 breast:3.67 salivary:2.43
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:0.61 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.43 pancreas:- breast:0.26 salivary:-

Gene Information

IDs

Refseq ID NM_017651
Gene ID 54806
Unigene ID Hs.386684
Probe set ID 220841_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000135541
GTEx ID ENSG00000135541

Orthologous Gene

Mouse[2]  NM_001177776, NM_026203
Rat[1]  NM_001002277, NM_026203

Chromosomal Region

6q23.3  [135,604,670  -  135,830,219]

Gene Family (Interpro ID)

IPR001680  WD40 repeat
IPR019782  WD40 repeat 2
IPR019781  WD40 repeat, subgroup
IPR011046  WD40 repeat-like-containing domain
IPR017986  WD40-repeat-containing domain
IPR015943  WD40/YVTN repeat-like-containing domain

Link to Pubmed  (Pubmed ID)

8125298
11076863
11230166
12186888
12477932
14574404
14702039
14751929
15060101
15169551
15322546
15467982
15489334
15489336
16155189
16240161
16381901
16453322
16773125
17409309
17473831
17668382
18054307
18227995
18633336
18782849
18785627
18936234
19191019
19322201
19342780
19379585
20045148
20071346
20301500
20301743
20371615
20379614
20452750
20580033
20683928
20805890
21068128
21833088
22123816
22183070
22285701
22623184
22745667
23028714
23171462
23446755
23532844

Gene Ontology  (GO ID)

Biological Process

GO:0034613  cellular protein localization
GO:0007417  central nervous system development
GO:0042384  cilium assembly
GO:0060271  cilium morphogenesis
GO:0001947  heart looping
GO:0030902  hindbrain development
GO:0070121  Kupffer's vesicle development
GO:0070986  left/right axis specification
GO:0001738  morphogenesis of a polarized epithelium
GO:0043066  negative regulation of apoptosis
GO:0030862  positive regulation of polarized epithelial cell differentiation
GO:0002092  positive regulation of receptor internalization
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0033365  protein localization in organelle
GO:0050795  regulation of behavior
GO:0010842  retina layer formation
GO:0065001  specification of axis polarity
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016192  vesicle-mediated transport

Cellular Component

GO:0005912  adherens junction
GO:0005911  cell-cell junction
GO:0005814  centriole
GO:0005813  centrosome
GO:0005929  cilium
GO:0005932  microtubule basal body
GO:0031513  nonmotile primary cilium

Molecular Function

GO:0005515  protein binding