adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

 jump to detail

Synonym

FLJ10659, DIP13 beta, DIP13B

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:30.80 cerebellum:12.60 brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:47 artery/aorta:- vein:- lymphnode:40.40 peripheral blood:18.20 spleen:18.90 thymus:25.80 bone marrow:78.70 adipose:40.30 bone:38.40 skin:52.80
GeneChip cerebrum:5.23 cerebellum:5.38 brain stem:5.26 corpus callosum/glia:5.64 pineal gland:- peripheral nerve:5.26 spine:5.91 retina:- eye:- artery/aorta:5.11 vein:4.82 lymphnode:4.90 peripheral blood:- spleen:5.09 thymus:5.70 bone marrow:4.87 adipose:5.55 bone:- skin:6.36
CAGE cerebrum:3.51 cerebellum:- brain stem:3.47 corpus callosum/glia:3.74 pineal gland:3.60 peripheral nerve:- spine:4.04 retina:- eye:- artery/aorta:3.50 vein:3.07 lymphnode:3.11 peripheral blood:- spleen:2.73 thymus:2.99 bone marrow:- adipose:3.34 bone:- skin:-
RNA-seq cerebrum:3.18 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.96 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.73 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:82 placenta:36.40 prostate:45.10 ovary:- testis:103.80 heart:89.40 muscle:- esophagus:- stomach:42.50 intestine:- colon:110.20     liver/hepato:-        lung:24.40    bladder:- kidney:93.60 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:44.50 breast:74.30 salivary:-
GeneChip uterus:5.99 placenta:6 prostate:7.35 ovary:5.82 testis:6.58 heart:4.84 muscle:4.49 esophagus:5.49 stomach:5.24 intestine:5.08 colon:5.23 liver/hepato:4.73 lung:4.85 bladder:- kidney:5.09 pituitary:5.54 thyroid/parathyroid:4.97 adrenal gland:5.16 pancreas:5.29 breast:6.02 salivary:4.94
CAGE uterus:3.39 placenta:3.35 prostate:3.30 ovary:3.00 testis:3.79 heart:3.07 muscle:2.96 esophagus:2.77 stomach:- intestine:4.26 colon:3.81     liver/hepato:2.79    lung:3.10 bladder:2.74 kidney:2.95 pituitary:3.26 thyroid/parathyroid:2.75 adrenal gland:- pancreas:3.47 breast:3.99 salivary:2.53
RNA-seq uterus:- placenta:- prostate:3.63 ovary:3.74 testis:4.00 heart:2.74 muscle:2.19 esophagus:- stomach:- intestine:- colon:2.89     liver/hepato:2.50        lung:3.17    bladder:- kidney:3.63 pituitary:- thyroid/parathyroid:2.99 adrenal gland:2.92 pancreas:- breast:3.22 salivary:-

Gene Information

IDs

Refseq ID NM_018171
Gene ID 55198
Unigene ID Hs.506603
Probe set ID 218218_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000136044
GTEx ID ENSG00000136044

Orthologous Gene

Mouse[1]  NM_145220
Rat[1]  NM_001108741

Chromosomal Region

12q23.3  [105,567,074  -  105,630,016]

Gene Family (Interpro ID)

IPR006020  Phosphotyrosine interaction domain
IPR001849  Pleckstrin homology
IPR011993  Pleckstrin homology-type

Link to Pubmed  (Pubmed ID)

11431708
12477932
14702039
15016378
15489334
16189514
16622416
17030088
18034774
19056867
19433865
20814572
21044950
21645192
22340213
22462604
22863883
22989406
23055524
23455924
23977033

Gene Ontology  (GO ID)

Biological Process

GO:0007049  cell cycle
GO:0008283  cell proliferation
GO:0007165  signal transduction

Cellular Component

GO:0005737  cytoplasm
GO:0031901  early endosome membrane
GO:0010008  endosome membrane
GO:0005634  nucleus
GO:0016581  NuRD complex

Molecular Function

GO:0005543  phospholipid binding
GO:0005515  protein binding