polymerase (RNA) III (DNA directed) polypeptide B

 jump to detail

Synonym

RPC2, RNA polymerase III subunit 2, FLJ10388, POLR3B, polymerase (RNA) III (DNA directed) polypeptide B

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:52.10 cerebellum:63 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:11.80 artery/aorta:30 vein:- lymphnode:- peripheral blood:- spleen:18.90 thymus:25.80 bone marrow:19.70 adipose:- bone:25.60 skin:19.20
GeneChip cerebrum:5.44 cerebellum:5.01 brain stem:5.43 corpus callosum/glia:5.36 pineal gland:- peripheral nerve:5.77 spine:5.51 retina:- eye:- artery/aorta:5.40 vein:5.53 lymphnode:5.38 peripheral blood:- spleen:5.24 thymus:5.39 bone marrow:5.37 adipose:5.50 bone:- skin:5.88
CAGE cerebrum:2.58 cerebellum:- brain stem:2.56 corpus callosum/glia:2.51 pineal gland:2.03 peripheral nerve:- spine:2.33 retina:- eye:- artery/aorta:1.82 vein:2.01 lymphnode:2.62 peripheral blood:- spleen:2.17 thymus:2.51 bone marrow:- adipose:2.19 bone:- skin:-
RNA-seq cerebrum:0.95 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.77 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.91 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:43.70 prostate:22.50 ovary:- testis:134.10 heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:67.80     liver/hepato:-        lung:19.60    bladder:- kidney:10.40 pituitary:347.90 thyroid/parathyroid:- adrenal gland:50.80 pancreas:- breast:27.90 salivary:-
GeneChip uterus:5.57 placenta:6.38 prostate:5.74 ovary:5.69 testis:5.56 heart:5.53 muscle:5.84 esophagus:6.11 stomach:5.39 intestine:5.49 colon:5.12 liver/hepato:6.12 lung:5.26 bladder:- kidney:5.69 pituitary:5.56 thyroid/parathyroid:5.36 adrenal gland:5.90 pancreas:5.57 breast:5.85 salivary:5.14
CAGE uterus:2.58 placenta:3.34 prostate:2.13 ovary:2.76 testis:2.56 heart:2.22 muscle:2.21 esophagus:2.47 stomach:- intestine:2.11 colon:1.75     liver/hepato:2.95    lung:2.03 bladder:1.92 kidney:2.35 pituitary:2.82 thyroid/parathyroid:2.05 adrenal gland:- pancreas:2.34 breast:2.02 salivary:2.17
RNA-seq uterus:- placenta:- prostate:0.78 ovary:2.17 testis:1.24 heart:0.94 muscle:0.84 esophagus:- stomach:- intestine:- colon:0.28     liver/hepato:0.49        lung:0.18    bladder:- kidney:0.22 pituitary:- thyroid/parathyroid:2.07 adrenal gland:1.00 pancreas:- breast:1.50 salivary:-

Gene Information

IDs

Refseq ID NM_018082
Gene ID 55703
Unigene ID Hs.62696
Probe set ID 219459_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000013503
GTEx ID ENSG00000013503

Orthologous Gene

Mouse[1]  NM_027423
Rat [0]  

Chromosomal Region

12q23.3  [106,751,436  -  106,903,976]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1403646
12391170
12477932
14702039
15489334
16344560
17643375
17903297
19331820
19609254
19615732
19631370
20379614
21139048
21890473
21906983
21963094
22036171
22036172
22855961
22889924
22939629
23124897
23355746
24250222
24501781
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0051607  defense response to virus
GO:0010467  gene expression
GO:0045087  innate immune response
GO:0045089  positive regulation of innate immune response
GO:0032728  positive regulation of interferon-beta production
GO:0032481  positive regulation of type I interferon production
GO:0006385  RNA elongation from RNA polymerase III promoter
GO:0006386  termination of RNA polymerase III transcription
GO:0006383  transcription from RNA polymerase III promoter

Cellular Component

GO:0005829  cytosol
GO:0005654  nucleoplasm

Molecular Function

GO:0003677  DNA binding
GO:0003899  DNA-directed RNA polymerase activity
GO:0046872  metal ion binding
GO:0032549  ribonucleoside binding