mitogen-activated protein kinase 9

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Synonym

JNK2B, c-Jun N-terminal kinase 2, JNK2, JNK-55, mitogen-activated protein kinase 9, JNK2BETA, MAPK9, p54aSAPK, Mitogen-activated protein kinase 9, Stress-activated protein kinase JNK2, JNK2ALPHA, PRKM9, JNK2A, Jun kinase

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:75.80 cerebellum:63 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:88.20 artery/aorta:- vein:199.90 lymphnode:30.30 peripheral blood:36.40 spleen:- thymus:12.90 bone marrow:19.70 adipose:- bone:25.60 skin:57.60
GeneChip cerebrum:6.04 cerebellum:6.43 brain stem:6.41 corpus callosum/glia:5.41 pineal gland:- peripheral nerve:5.81 spine:5.83 retina:- eye:- artery/aorta:5.31 vein:5.33 lymphnode:5.17 peripheral blood:- spleen:5.16 thymus:5.10 bone marrow:5.59 adipose:5.66 bone:- skin:5.44
CAGE cerebrum:3.89 cerebellum:- brain stem:3.79 corpus callosum/glia:3.26 pineal gland:2.42 peripheral nerve:- spine:3.30 retina:- eye:- artery/aorta:2.96 vein:2.57 lymphnode:2.63 peripheral blood:- spleen:2.89 thymus:2.75 bone marrow:- adipose:2.70 bone:- skin:-
RNA-seq cerebrum:2.06 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.01 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:69.20 prostate:33.80 ovary:37.30 testis:51.90 heart:12.80 muscle:120.50 esophagus:- stomach:21.20 intestine:32.40 colon:67.80     liver/hepato:73.90        lung:92.90    bladder:- kidney:93.60 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:55.80 salivary:-
GeneChip uterus:5.26 placenta:6.02 prostate:5.44 ovary:5 testis:5.37 heart:5.73 muscle:5.47 esophagus:5.61 stomach:5.69 intestine:5.66 colon:5.76 liver/hepato:4.99 lung:5.08 bladder:- kidney:5.52 pituitary:5.25 thyroid/parathyroid:5.20 adrenal gland:5.35 pancreas:6 breast:5.20 salivary:5.59
CAGE uterus:2.74 placenta:3.06 prostate:3.00 ovary:2.81 testis:2.88 heart:3.02 muscle:2.85 esophagus:2.75 stomach:- intestine:2.92 colon:2.92     liver/hepato:2.63    lung:3.02 bladder:2.98 kidney:2.74 pituitary:2.63 thyroid/parathyroid:2.99 adrenal gland:- pancreas:3.57 breast:3.45 salivary:3.08
RNA-seq uterus:- placenta:- prostate:0.02 ovary:0.01 testis:0.00 heart:0.01 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.01     liver/hepato:0.00        lung:0    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.17 pancreas:- breast:0.00 salivary:-

IDs

Refseq ID NM_139069
Gene ID 5601
Unigene ID Hs.484371
Probe set ID 210570_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000050748
GTEx ID ENSG00000050748

Orthologous Gene

Mouse[12]  NM_001163671, NM_001163672, NM_016961, NM_207692
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

602896
1602151
7642542
7737129
7969172
8001819
8548291
8626452
8649858
8654373
8846788
8945519
8985011
9019171
9045910
9130707
9155018
9374467
9393873
9403476
9405416
9628874
9732264
9733513
10376527
10381549
10383391
10471813
10490605
10490659
10523642
10629060
10669748
10797012
10811224
10878576
11024282
11042694
11057897
11062067
11172026
11278395
11278789
11279232
11359773
11468147
11504923
11527157
11566021
11602244
11698270
11749722
11948398
11959861
12023963
12089333
12110590
12151396
12167088
12171600
12189133
12225289
12228228
12239168
12384512
12417588
12477932
12538493
12714584
12743126
12775419
12788955
12818176
12821118
12857973
12960231
14504284
14581471
14724588
15158451
15184502
15246824
15262983
15276183
15326485
15474087
15489334
15527495
15603708
15629715
15637069
15655348
15693750
15778501
15860507
15911620
15998799
16169070
16189514
16381010
16412424
16481105
16533805
16552729
16611996
16824735
17074809
17189706
17192257
17296730
17397142
17637567
17785791
17875713
17908987
18262097
18423204
18439101
18586006
18612143
18801372
18838864
18940813
18950845
19060904
19093167
19097143
19153595
19154785
19204086
19339050
19385049
19527717
19567513
19589256
19591174
19596001
19620725
19651615
19667122
19806201
19864026
19906316
19910486
19913278
19996270
20056178
20174665
20354187
20379614
20432452
20483637
20525557
20595622
20871632
20936779
21110917
21139048
21357683
21364637
21384452
21504622
21572099
21629969
21749326
21890473
21900206
21906983
21988832
22105759
22217202
22366412
22505724
22689214
22730327
22748923
22910906
22939629
23045269
23071284
23171849
23273084
23341463
23515281
23602568
23615449
23900581
23912840
24335928
24447338
24704364
24722904
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0071363  cellular response to growth factor stimulus
GO:0071347  cellular response to interleukin-1
GO:0071222  cellular response to lipopolysaccharide
GO:0071356  cellular response to tumor necrosis factor
GO:0034644  cellular response to UV
GO:0007417  central nervous system development
GO:0045087  innate immune response
GO:0007254  JNK cascade
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0002756  MyD88-independent toll-like receptor signaling pathway
GO:0031175  neuron projection development
GO:0043065  positive regulation of apoptosis
GO:0010770  positive regulation of cell morphogenesis involved in differentiation
GO:0032722  positive regulation of chemokine production
GO:0010628  positive regulation of gene expression
GO:0010744  positive regulation of macrophage derived foam cell differentiation
GO:0045429  positive regulation of nitric oxide biosynthetic process
GO:0051770  positive regulation of nitric-oxide synthase biosynthetic process
GO:0031394  positive regulation of prostaglandin biosynthetic process
GO:0032308  positive regulation of prostaglandin secretion
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006626  protein targeting to mitochondrion
GO:0046328  regulation of JNK cascade
GO:0031396  regulation of protein ubiquitination
GO:0051090  regulation of transcription factor activity
GO:0001836  release of cytochrome c from mitochondria
GO:0014075  response to amine stimulus
GO:0046686  response to cadmium ion
GO:0042493  response to drug
GO:0009612  response to mechanical stimulus
GO:0006950  response to stress
GO:0009636  response to toxin
GO:0051403  stress-activated MAPK cascade
GO:0034166  toll-like receptor 10 signaling pathway
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034146  toll-like receptor 5 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0005829  cytosol
GO:0005739  mitochondrion
GO:0005654  nucleoplasm

Molecular Function

GO:0005524  ATP binding
GO:0008656  caspase activator activity
GO:0004705  JUN kinase activity
GO:0031435  mitogen-activated protein kinase kinase kinase binding
GO:0005515  protein binding
GO:0008134  transcription factor binding