potassium channel, subfamily K, member 12

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Synonym

Potassium channel subfamily K member 12, THIK2, potassium channel, subfamily K, member 12, THIK-2, KCNK12

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:9.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:5.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:12.90 bone marrow:39.40 adipose:- bone:- skin:4.80
GeneChip cerebrum:5.41 cerebellum:6.32 brain stem:5.39 corpus callosum/glia:4.90 pineal gland:- peripheral nerve:7.64 spine:5.84 retina:- eye:- artery/aorta:4.15 vein:4.09 lymphnode:4.18 peripheral blood:- spleen:3.69 thymus:4.11 bone marrow:4.21 adipose:4.07 bone:- skin:4.24
CAGE cerebrum:2.88 cerebellum:- brain stem:3.18 corpus callosum/glia:2.27 pineal gland:2.40 peripheral nerve:- spine:2.97 retina:- eye:- artery/aorta:0 vein:0.70 lymphnode:0.67 peripheral blood:- spleen:0.09 thymus:0.99 bone marrow:- adipose:0.55 bone:- skin:-
RNA-seq cerebrum:0.76 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.30 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.14 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:10.90 prostate:- ovary:- testis:13 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:10.60        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:71.10 breast:- salivary:-
GeneChip uterus:4.04 placenta:4.27 prostate:3.88 ovary:3.93 testis:4.35 heart:3.96 muscle:4.14 esophagus:4.01 stomach:4 intestine:4.16 colon:4.26 liver/hepato:3.80 lung:3.63 bladder:- kidney:4.03 pituitary:5.27 thyroid/parathyroid:3.64 adrenal gland:4.11 pancreas:4.49 breast:3.82 salivary:4.05
CAGE uterus:0.09 placenta:0.81 prostate:0.39 ovary:0.07 testis:0.71 heart:0.28 muscle:0.09 esophagus:0.86 stomach:- intestine:0.07 colon:0.53     liver/hepato:0    lung:0 bladder:0.18 kidney:0.15 pituitary:2.94 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0.36
RNA-seq uterus:- placenta:- prostate:0.20 ovary:0.02 testis:0.25 heart:0.07 muscle:0.04 esophagus:- stomach:- intestine:- colon:0.04     liver/hepato:0        lung:0.02    bladder:- kidney:0.02 pituitary:- thyroid/parathyroid:0.01 adrenal gland:0.05 pancreas:- breast:0.01 salivary:-

Gene Information

IDs

Refseq ID NM_022055
Gene ID 56660
Unigene ID Hs.591586
Probe set ID 220448_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000184261
GTEx ID ENSG00000184261

Orthologous Gene

Mouse[1]  NM_199251
Rat[1]  NM_022292

Chromosomal Region

2p21  [47,747,910  -  47,798,078]

Gene Family (Interpro ID)

IPR003280  Potassium channel, two pore-domain

Link to Pubmed  (Pubmed ID)

11060316
11256078
11263999
12477932
15489334
17081983
18209473
18676988
19890347
24163367

Gene Ontology  (GO ID)

Cellular Component

GO:0016021  integral to membrane

Molecular Function

GO:0005267  potassium channel activity
GO:0005244  voltage-gated ion channel activity