pyridoxal (pyridoxine, vitamin B6) phosphatase

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Synonym

PLPP, PDXP, CIN, dJ37E16.5, PLP phosphatase, Pyridoxal phosphate phosphatase, FLJ32703, pyridoxal (pyridoxine, vitamin B6) phosphatase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:75.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:- spine:- retina:- eye:29.40 artery/aorta:- vein:- lymphnode:40.40 peripheral blood:- spleen:- thymus:38.70 bone marrow:118.10 adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:3.74 cerebellum:- brain stem:2.83 corpus callosum/glia:2.74 pineal gland:2.58 peripheral nerve:- spine:2.40 retina:- eye:- artery/aorta:1.43 vein:1.73 lymphnode:1.70 peripheral blood:- spleen:1.97 thymus:2.32 bone marrow:- adipose:1.16 bone:- skin:-
RNA-seq cerebrum:5.08 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.98 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.39 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:32.80 prostate:11.30 ovary:- testis:26 heart:140.50 muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:21.10        lung:4.90    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:44.50 breast:9.30 salivary:-
GeneChip nodata
CAGE uterus:1.20 placenta:1.02 prostate:1.49 ovary:1.73 testis:2.72 heart:1.78 muscle:1.46 esophagus:1.44 stomach:- intestine:3.43 colon:2.75     liver/hepato:3.16    lung:1.52 bladder:1.52 kidney:1.46 pituitary:1.99 thyroid/parathyroid:1.50 adrenal gland:- pancreas:1.42 breast:1.80 salivary:1.49
RNA-seq uterus:- placenta:- prostate:2.64 ovary:2.56 testis:3.61 heart:2.58 muscle:2.55 esophagus:- stomach:- intestine:- colon:2.55     liver/hepato:4.49        lung:2.04    bladder:- kidney:2.12 pituitary:- thyroid/parathyroid:1.69 adrenal gland:2.36 pancreas:- breast:1.82 salivary:-

Gene Information

IDs

Refseq ID NM_020315
Gene ID 57026
Unigene ID Hs.632762
Probe set ID -
Ensembl ID ENSG00000241360
GTEx ID ENSG00000241360

Orthologous Gene

Mouse[2]  NM_020271
Rat [0]  

Chromosomal Region

22q13.1  [38,054,734  -  38,062,941]

Gene Family (Interpro ID)

IPR006349  2-phosphoglycolate phosphatase, eukaryotic
IPR006357  HAD-superfamily hydrolase, subfamily IIA

Link to Pubmed  (Pubmed ID)

8132548
10591208
12477932
14522954
14702039
15489334
15580268
16336786
17500066
18029348
18510874
19000834
21139048
21897333
22939629
23223568

Gene Ontology  (GO ID)

Biological Process

GO:0031247  actin rod formation
GO:0071318  cellular response to ATP
GO:0030836  positive regulation of actin filament depolymerization
GO:0006470  protein amino acid dephosphorylation
GO:0032465  regulation of cytokinesis
GO:0007088  regulation of mitosis

Cellular Component

GO:0015629  actin cytoskeleton
GO:0032154  cleavage furrow
GO:0070938  contractile ring
GO:0005829  cytosol
GO:0030027  lamellipodium
GO:0031258  lamellipodium membrane
GO:0030496  midbody
GO:0005886  plasma membrane
GO:0032587  ruffle membrane

Molecular Function

GO:0031072  heat shock protein binding
GO:0046872  metal ion binding
GO:0004721  phosphoprotein phosphatase activity
GO:0004647  phosphoserine phosphatase activity
GO:0005515  protein binding
GO:0033883  pyridoxal phosphatase activity