proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

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Synonym

26S proteasome regulatory subunit S14, Nin1p, HIP6, S14, PSMD8, HYPF, MGC1660, 26S proteasome non-ATPase regulatory subunit 8, p31

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:8.15 cerebellum:8.10 brain stem:8.22 corpus callosum/glia:7.91 pineal gland:- peripheral nerve:8.81 spine:7.99 retina:- eye:- artery/aorta:8.17 vein:8.51 lymphnode:7.95 peripheral blood:- spleen:7.57 thymus:8.61 bone marrow:7.92 adipose:8.92 bone:- skin:8.85
CAGE cerebrum:5.02 cerebellum:- brain stem:4.81 corpus callosum/glia:4.78 pineal gland:4.77 peripheral nerve:- spine:4.65 retina:- eye:- artery/aorta:4.88 vein:5.01 lymphnode:4.94 peripheral blood:- spleen:4.82 thymus:4.98 bone marrow:- adipose:5.38 bone:- skin:-
RNA-seq cerebrum:4.83 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.13 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.94 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:8.24 placenta:8.73 prostate:8.91 ovary:8.53 testis:9.65 heart:8.57 muscle:8.80 esophagus:9.05 stomach:7.82 intestine:8.41 colon:8.11 liver/hepato:7.69 lung:8.26 bladder:- kidney:8.22 pituitary:7.81 thyroid/parathyroid:8.11 adrenal gland:7.92 pancreas:8.48 breast:8.55 salivary:8.27
CAGE uterus:4.62 placenta:5.44 prostate:4.78 ovary:4.72 testis:5.63 heart:5.47 muscle:6.30 esophagus:5.15 stomach:- intestine:4.99 colon:5.01     liver/hepato:5.60    lung:4.86 bladder:4.86 kidney:5.19 pituitary:4.78 thyroid/parathyroid:5.01 adrenal gland:- pancreas:5.30 breast:5.29 salivary:4.99
RNA-seq uterus:- placenta:- prostate:5.48 ovary:4.90 testis:5.91 heart:5.97 muscle:7.03 esophagus:- stomach:- intestine:- colon:4.90     liver/hepato:5.54        lung:5.47    bladder:- kidney:5.53 pituitary:- thyroid/parathyroid:5.60 adrenal gland:5.26 pancreas:- breast:5.59 salivary:-

Gene Information

IDs

Refseq ID NM_002812
Gene ID 5714
Unigene ID -
Probe set ID 200820_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000099341
GTEx ID ENSG00000099341

Orthologous Gene

Mouse[1]  NM_026545
Rat[1]  NM_001100831

Chromosomal Region

19q13.2  [38,865,176  -  38,874,464]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7621825
8811196
9079628
9811770
9846577
10225950
10893419
11163772
11285280
12167863
12419264
12477932
12719574
12750511
12791267
12808465
12808466
12809610
12830140
12840737
12859895
12914693
12920286
12970355
14527406
14528300
14528301
14550573
14557625
14564014
14614829
15029244
15057824
15231748
15342556
15489334
15831487
16196087
16239144
16885229
17323924
17353931
17558393
17786314
18029348
18775730
19013454
19193609
19471022
20004025
20542005
20972266
21139048
21319273
21628461
21693764
21767633
21890473
21906983
21963094
21987572
22118674
22275368
22505724
22797925
22863883
22906049
22939629
22990118
23000965
23438482
23503661
23751493
23824909
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0031145  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0042590  antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474  antigen processing and presentation of peptide antigen via MHC class I
GO:0006915  apoptosis
GO:0034641  cellular nitrogen compound metabolic process
GO:0006977  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0000082  G1/S transition of mitotic cell cycle
GO:0010467  gene expression
GO:0000278  mitotic cell cycle
GO:0016071  mRNA metabolic process
GO:0043066  negative regulation of apoptosis
GO:0051436  negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0051437  positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0000209  protein polyubiquitination
GO:0042981  regulation of apoptosis
GO:0006521  regulation of cellular amino acid metabolic process
GO:0051439  regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0016070  RNA metabolic process
GO:0016032  viral reproduction

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0022624  proteasome accessory complex
GO:0000502  proteasome complex
GO:0005838  proteasome regulatory particle