zinc finger, FYVE domain containing 28

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Synonym

zinc finger, FYVE domain containing 28, Zinc finger FYVE domain-containing protein 28, MGC61592, KIAA1643, MGC43699, ZFYVE28

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:19 cerebellum:176.30 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:29.40 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:- spleen:18.90 thymus:12.90 bone marrow:- adipose:80.70 bone:- skin:14.40
GeneChip nodata
CAGE cerebrum:3.30 cerebellum:- brain stem:2.98 corpus callosum/glia:2.48 pineal gland:2.94 peripheral nerve:- spine:3.17 retina:- eye:- artery/aorta:2.59 vein:1.89 lymphnode:2.05 peripheral blood:- spleen:1.82 thymus:1.33 bone marrow:- adipose:2.07 bone:- skin:-
RNA-seq cerebrum:1.42 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.25 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:3.60 prostate:- ovary:74.50 testis:51.90 heart:- muscle:- esophagus:- stomach:42.50 intestine:32.40 colon:33.90     liver/hepato:-        lung:19.60    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:62.20 breast:- salivary:-
GeneChip nodata
CAGE uterus:2.00 placenta:0.77 prostate:1.87 ovary:1.51 testis:2.34 heart:1.97 muscle:1.26 esophagus:1.70 stomach:- intestine:2.97 colon:2.63     liver/hepato:1.54    lung:2.14 bladder:1.64 kidney:2.07 pituitary:2.92 thyroid/parathyroid:1.55 adrenal gland:- pancreas:1.87 breast:2.19 salivary:2.26
RNA-seq uterus:- placenta:- prostate:0.45 ovary:0.24 testis:0.18 heart:0.28 muscle:0.16 esophagus:- stomach:- intestine:- colon:0.58     liver/hepato:0.52        lung:0.10    bladder:- kidney:1.40 pituitary:- thyroid/parathyroid:0.18 adrenal gland:0.00 pancreas:- breast:0.32 salivary:-

Gene Information

IDs

Refseq ID NM_020972
Gene ID 57732
Unigene ID Hs.292056
Probe set ID -
Ensembl ID ENSG00000159733
GTEx ID ENSG00000159733

Orthologous Gene

Mouse[1]  NM_001015039
Rat[1]  NM_001107227

Chromosomal Region

4p16.3  [2,271,309  -  2,420,390]

Gene Family (Interpro ID)

IPR000306  Zinc finger, FYVE-type
IPR011011  Zinc finger, FYVE/PHD-type
IPR013083  Zinc finger, RING/FYVE/PHD-type

Link to Pubmed  (Pubmed ID)

10997877
12477932
18482256
19460345
20379614
21890473
21906983
21963094
21987572
22505724
23000965
23212062
24324551

Gene Ontology  (GO ID)

Biological Process

GO:0007175  negative regulation of epidermal growth factor receptor activity
GO:0042059  negative regulation of epidermal growth factor receptor signaling pathway

Cellular Component

GO:0005829  cytosol
GO:0031901  early endosome membrane

Molecular Function

GO:0046872  metal ion binding
GO:0032266  phosphatidylinositol 3-phosphate binding
GO:0005515  protein binding