netrin 4

 jump to detail

Synonym

Beta-netrin, FLJ23180, Netrin-4 precursor, NTN4, netrin 4, PRO3091, Hepar-derived netrin-like protein

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:32 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:61.30 spine:112.30 retina:- eye:35.30 artery/aorta:299.80 vein:- lymphnode:10.10 peripheral blood:- spleen:94.50 thymus:25.80 bone marrow:19.70 adipose:80.70 bone:102.40 skin:52.80
GeneChip nodata
CAGE cerebrum:1.83 cerebellum:- brain stem:1.50 corpus callosum/glia:1.70 pineal gland:1.73 peripheral nerve:- spine:1.48 retina:- eye:- artery/aorta:3.64 vein:2.69 lymphnode:1.38 peripheral blood:- spleen:4.91 thymus:1.18 bone marrow:- adipose:3.03 bone:- skin:-
RNA-seq cerebrum:2.64 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.77 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.30 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:40.10 prostate:90.10 ovary:- testis:13 heart:51.10 muscle:60.30 esophagus:- stomach:21.20 intestine:- colon:8.50     liver/hepato:31.70        lung:78.20    bladder:125.60 kidney:218.30 pituitary:- thyroid/parathyroid:- adrenal gland:152.40 pancreas:17.80 breast:83.60 salivary:-
GeneChip nodata
CAGE uterus:2.88 placenta:2.58 prostate:3.81 ovary:3.35 testis:2.55 heart:3.83 muscle:2.30 esophagus:2.95 stomach:- intestine:2.79 colon:2.51     liver/hepato:3.05    lung:3.80 bladder:3.07 kidney:4.10 pituitary:1.45 thyroid/parathyroid:2.44 adrenal gland:- pancreas:2.81 breast:3.33 salivary:2.12
RNA-seq uterus:- placenta:- prostate:4.35 ovary:4.37 testis:3.57 heart:4.07 muscle:1.82 esophagus:- stomach:- intestine:- colon:3.91     liver/hepato:4.35        lung:4.13    bladder:- kidney:5.73 pituitary:- thyroid/parathyroid:3.02 adrenal gland:2.51 pancreas:- breast:4.45 salivary:-

Gene Information

IDs

Refseq ID NM_021229
Gene ID 59277
Unigene ID Hs.201034
Probe set ID -
Ensembl ID ENSG00000074527
GTEx ID ENSG00000074527

Orthologous Gene

Mouse[1]  NM_021320
Rat[1]  NM_001106780

Chromosomal Region

12q22  [96,051,583  -  96,184,930]

Gene Family (Interpro ID)

IPR001134  Netrin domain
IPR018933  Netrin module, non-TIMP type
IPR008993  TIMP-like, OB-fold

Link to Pubmed  (Pubmed ID)

11038171
12477932
14702039
15489334
15519678
16189514
17174565
17545519
18719102
19094984
19859801
20029409
20407033
20730893
21406174
21799154
22496621
22705235
23535729
23535733
23921680
24120501

Gene Ontology  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0030198  extracellular matrix organization
GO:0016322  neuron remodeling
GO:0060668  regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling

Cellular Component

GO:0005604  basement membrane
GO:0005886  plasma membrane

Molecular Function

GO:0043237  laminin-1 binding