RNA binding motif protein 4

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Synonym

RBM4, RNA-binding protein 4, RNA-binding motif protein 4a, RNA binding motif protein 4, Lark homolog, ZCRB3A, ZCCHC21, RBM4A, hLark, RNA-binding motif protein 4, LARK, DKFZp547K0918, MGC75138

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:282.10 cerebellum:302.30 brain stem:- corpus callosum/glia:349.90 pineal gland:296.70 peripheral nerve:122.70 spine:112.30 retina:118.60 eye:246.80 artery/aorta:299.80 vein:66.60 lymphnode:202.20 peripheral blood:291.50 spleen:397 thymus:798.80 bone marrow:216.50 adipose:121 bone:140.70 skin:225.60
GeneChip cerebrum:7.67 cerebellum:8.28 brain stem:7.48 corpus callosum/glia:7.76 pineal gland:- peripheral nerve:8.05 spine:7.68 retina:- eye:- artery/aorta:8.50 vein:7.95 lymphnode:8.47 peripheral blood:- spleen:8.74 thymus:8.79 bone marrow:8.12 adipose:7.99 bone:- skin:8.23
CAGE cerebrum:3.79 cerebellum:- brain stem:3.50 corpus callosum/glia:3.67 pineal gland:4.20 peripheral nerve:- spine:3.66 retina:- eye:- artery/aorta:3.77 vein:3.84 lymphnode:3.66 peripheral blood:- spleen:3.60 thymus:4.15 bone marrow:- adipose:3.80 bone:- skin:-
RNA-seq cerebrum:3.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.27 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.86 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:300.70 placenta:236.80 prostate:202.80 ovary:484.40 testis:281.20 heart:178.80 muscle:60.30 esophagus:1371.30 stomach:424.80 intestine:291.60 colon:178.10     liver/hepato:137.20        lung:234.60    bladder:376.80 kidney:187.10 pituitary:232 thyroid/parathyroid:163.70 adrenal gland:406.30 pancreas:249 breast:213.70 salivary:-
GeneChip uterus:8.61 placenta:8.14 prostate:8.79 ovary:8.77 testis:8.68 heart:7.82 muscle:7.95 esophagus:8.66 stomach:8.38 intestine:8.11 colon:8.24 liver/hepato:7.89 lung:8.67 bladder:- kidney:8.47 pituitary:8.32 thyroid/parathyroid:8.66 adrenal gland:8.48 pancreas:8.28 breast:8.58 salivary:8.59
CAGE uterus:3.77 placenta:3.75 prostate:3.73 ovary:3.75 testis:3.98 heart:3.43 muscle:3.61 esophagus:3.73 stomach:- intestine:3.50 colon:3.68     liver/hepato:3.42    lung:3.58 bladder:3.64 kidney:3.64 pituitary:3.79 thyroid/parathyroid:4.04 adrenal gland:- pancreas:4.05 breast:3.66 salivary:4.16
RNA-seq uterus:- placenta:- prostate:4.24 ovary:4.57 testis:5.08 heart:3.51 muscle:4.60 esophagus:- stomach:- intestine:- colon:4.36     liver/hepato:3.57        lung:5.06    bladder:- kidney:4.93 pituitary:- thyroid/parathyroid:3.99 adrenal gland:3.55 pancreas:- breast:3.97 salivary:-

Gene Information

IDs

Refseq ID NM_002896
Gene ID 5936
Unigene ID Hs.533712
Probe set ID 200997_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000173933
ENSG00000248643
GTEx ID ENSG00000173933
ENSG00000248643

Orthologous Gene

Mouse [0]  
Rat [0]  

Chromosomal Region

11q13.2  [66,384,097  -  66,413,940]
11q13.2  [66,406,088  -  66,434,153]

Gene Family (Interpro ID)

IPR000504  RNA recognition motif, RNP-1
IPR001878  Zinc finger, CCHC-type

Link to Pubmed  (Pubmed ID)

8125298
8889548
9169144
11790298
12469345
12477932
12508107
12628928
14702039
15159402
15231748
15489334
15592455
16260624
16344560
16777844
16907643
16934801
17284590
18276110
18708123
18723113
19416963
19471022
19561594
19738201
19801630
21139048
21145461
21518792
21562054
21890473
21926972
21963094
21987572
22365833
22505724
22623428
22939629
23000965
23527094
23667531
23897118
24332808
24389249
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0030154  cell differentiation
GO:0033554  cellular response to stress
GO:0043153  entrainment of circadian clock by photoperiod
GO:0006397  mRNA processing
GO:0017148  negative regulation of translation
GO:0032055  negative regulation of translation in response to stress
GO:0035278  negative regulation of translation involved in gene silencing by miRNA
GO:0045947  negative regulation of translational initiation
GO:0051149  positive regulation of muscle cell differentiation
GO:0000381  regulation of alternative nuclear mRNA splicing, via spliceosome
GO:0046822  regulation of nucleocytoplasmic transport
GO:0006396  RNA processing
GO:0008380  RNA splicing
GO:0051403  stress-activated MAPK cascade

Cellular Component

GO:0005737  cytoplasm
GO:0016607  nuclear speck
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0010494  stress granule

Molecular Function

GO:0035198  miRNA binding
GO:0003730  mRNA 3'-UTR binding
GO:0003729  mRNA binding
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0003723  RNA binding
GO:0008270  zinc ion binding