retinol dehydrogenase 5 (11-cis/9-cis)

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Synonym

RDH1, 11-cis retinol dehydrogenase, retinol dehydrogenase 5 (11-cis/9-cis), 11-cis RDH, retinol dehydrogenase 5 (11-cis and 9-cis), RDH5

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.80 skin:-
GeneChip cerebrum:5.47 cerebellum:5.39 brain stem:5.63 corpus callosum/glia:5.48 pineal gland:- peripheral nerve:5.59 spine:5.41 retina:- eye:- artery/aorta:6.61 vein:6.54 lymphnode:5.64 peripheral blood:- spleen:5.43 thymus:5.05 bone marrow:5.47 adipose:7.71 bone:- skin:5.95
CAGE cerebrum:0.36 cerebellum:- brain stem:0.53 corpus callosum/glia:0.85 pineal gland:1.43 peripheral nerve:- spine:0.80 retina:- eye:- artery/aorta:2.28 vein:2.97 lymphnode:0.90 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:4.18 bone:- skin:-
RNA-seq cerebrum:0.36 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.01 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.83 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:- prostate:- ovary:- testis:4.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.33 placenta:5.12 prostate:5.20 ovary:5.20 testis:5.56 heart:5.90 muscle:6.30 esophagus:5.61 stomach:5.52 intestine:5.79 colon:6.06 liver/hepato:6.55 lung:5.29 bladder:- kidney:5.85 pituitary:5.51 thyroid/parathyroid:5.34 adrenal gland:5.55 pancreas:5.74 breast:6.17 salivary:5.34
CAGE uterus:1.04 placenta:0.16 prostate:1.28 ovary:1.06 testis:0.46 heart:1.71 muscle:1.86 esophagus:1.54 stomach:- intestine:2.88 colon:2.65     liver/hepato:3.04    lung:0.64 bladder:1.40 kidney:1.66 pituitary:0.19 thyroid/parathyroid:0.73 adrenal gland:- pancreas:0 breast:3.40 salivary:0
RNA-seq uterus:- placenta:- prostate:0.40 ovary:0.54 testis:0.96 heart:0.22 muscle:0.84 esophagus:- stomach:- intestine:- colon:0.41     liver/hepato:1.06        lung:0.31    bladder:- kidney:0.52 pituitary:- thyroid/parathyroid:1.21 adrenal gland:0.16 pancreas:- breast:5.86 salivary:-

Gene Information

IDs

Refseq ID NM_002905
Gene ID 5959
Unigene ID Hs.600940
Probe set ID 210106_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000135437
GTEx ID ENSG00000135437

Orthologous Gene

Mouse[1]  NM_134006
Rat[1]  NM_134006

Chromosomal Region

12q13.2  [56,114,151  -  56,118,489]

Gene Family (Interpro ID)

IPR003560  2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
IPR002347  Glucose/ribitol dehydrogenase
IPR002198  Short-chain dehydrogenase/reductase SDR

Link to Pubmed  (Pubmed ID)

7836368
8884265
8889548
9115228
9931293
10369264
10617778
11053295
11078852
11274198
11470705
11675386
11812441
12226107
12477932
12536149
12732844
12788147
12860821
12906118
12967826
14702039
15007239
15302662
15342556
15489334
15790919
16637847
17207965
17286855
17476461
18363170
18949499
19027726
19322201
19460752
20382160
20618457
20801113
20801516
20829743
21529959
22669287
22736946
22815624
23396134
24246574

Gene Ontology  (GO ID)

Biological Process

GO:0007603  phototransduction, visible light
GO:0001523  retinoid metabolic process
GO:0042572  retinol metabolic process
GO:0007601  visual perception

Cellular Component

GO:0005788  endoplasmic reticulum lumen
GO:0005789  endoplasmic reticulum membrane

Molecular Function

GO:0004745  retinol dehydrogenase activity