rhotekin

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Synonym

rhotekin, Rhotekin, RTKN

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:80.60 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:47 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:18.90 thymus:- bone marrow:39.40 adipose:- bone:12.80 skin:52.80
GeneChip nodata
CAGE cerebrum:3.57 cerebellum:- brain stem:4.41 corpus callosum/glia:4.82 pineal gland:1.38 peripheral nerve:- spine:4.08 retina:- eye:- artery/aorta:1.94 vein:2.29 lymphnode:1.73 peripheral blood:- spleen:1.02 thymus:1.47 bone marrow:- adipose:1.79 bone:- skin:-
RNA-seq cerebrum:1.96 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.36 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.24 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:14.60 prostate:33.80 ovary:37.30 testis:13 heart:51.10 muscle:- esophagus:- stomach:42.50 intestine:64.80 colon:59.40     liver/hepato:-        lung:14.70    bladder:125.60 kidney:156 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:97.80 breast:55.80 salivary:-
GeneChip nodata
CAGE uterus:2.10 placenta:2.22 prostate:2.54 ovary:2.09 testis:1.42 heart:2.12 muscle:0.97 esophagus:2.77 stomach:- intestine:3.30 colon:2.91     liver/hepato:4.16    lung:2.34 bladder:1.91 kidney:3.42 pituitary:2.26 thyroid/parathyroid:2.71 adrenal gland:- pancreas:3.20 breast:2.27 salivary:3.46
RNA-seq uterus:- placenta:- prostate:0.87 ovary:0.42 testis:0.56 heart:0.62 muscle:0.75 esophagus:- stomach:- intestine:- colon:0.85     liver/hepato:0.00        lung:0.21    bladder:- kidney:0.79 pituitary:- thyroid/parathyroid:0.75 adrenal gland:0.87 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_001015056
Gene ID 6242
Unigene ID Hs.192854
Probe set ID -
Ensembl ID ENSG00000114993
GTEx ID ENSG00000114993

Orthologous Gene

Mouse[3]  NM_001136227, NM_009106, NM_133641
Rat[1]  NM_184046, NM_009106, NM_133641

Chromosomal Region

2p13.1  [74,652,963  -  74,669,549]

Gene Family (Interpro ID)

IPR011072  HR1 rho-binding repeat
IPR000861  HR1-like rho-binding repeat
IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

8662891
9073523
9847074
10873388
10940294
12477932
12516569
12593858
12879077
14506264
15075243
15316142
15467718
15480428
15489334
15599595
15652748
15694321
15761153
15766663
15834426
15889147
16007136
16646955
16979770
17546647
18854161
19294487
19360360
19805522
20171953
21832049
21906983
22228765
22964635
24255178

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0007266  Rho protein signal transduction
GO:0007165  signal transduction

Cellular Component

GO:0005575  cellular_component

Molecular Function

GO:0005525  GTP binding
GO:0017049  GTP-Rho binding
GO:0005095  GTPase inhibitor activity
GO:0005543  phospholipid binding
GO:0005515  protein binding