sodium channel, voltage gated, type VIII, alpha subunit

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Synonym

voltage gated, Sodium channel protein type 8 subunit alpha, type VIII, sodium channel, voltage gated, type VIII, alpha, Sodium channel protein type VIII subunit alpha, Nav1.6, SCN8A, Voltage-gated sodium channel subunit alpha Nav1.6

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.29 cerebellum:4.83 brain stem:5.22 corpus callosum/glia:4.34 pineal gland:- peripheral nerve:4.83 spine:4.55 retina:- eye:- artery/aorta:4.57 vein:4.82 lymphnode:4.31 peripheral blood:- spleen:4.36 thymus:4.22 bone marrow:4.62 adipose:4.64 bone:- skin:4.61
CAGE cerebrum:4.00 cerebellum:- brain stem:2.55 corpus callosum/glia:2.34 pineal gland:3.29 peripheral nerve:- spine:2.49 retina:- eye:- artery/aorta:0.79 vein:0.70 lymphnode:0.43 peripheral blood:- spleen:0.71 thymus:0.88 bone marrow:- adipose:0.55 bone:- skin:-
RNA-seq cerebrum:2.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:4.32 placenta:4.23 prostate:4.24 ovary:4.41 testis:4.50 heart:4.38 muscle:4.66 esophagus:4.24 stomach:4.36 intestine:4.35 colon:4.45 liver/hepato:4.61 lung:4.15 bladder:- kidney:4.42 pituitary:4.88 thyroid/parathyroid:4.33 adrenal gland:4.48 pancreas:4.84 breast:4.33 salivary:4.52
CAGE uterus:0.53 placenta:0.30 prostate:0.66 ovary:0.72 testis:1.58 heart:0.28 muscle:0.09 esophagus:0.33 stomach:- intestine:0.21 colon:0.73     liver/hepato:1.29    lung:0.22 bladder:0.33 kidney:0.92 pituitary:3.50 thyroid/parathyroid:0.57 adrenal gland:- pancreas:0 breast:1.16 salivary:1.00
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:0.00 heart:0.00 muscle:0 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_014191
Gene ID 6334
Unigene ID -
Probe set ID 207049_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000196876
GTEx ID ENSG00000196876

Orthologous Gene

Mouse[4]  NM_001077499, NM_011323
Rat [0]  

Chromosomal Region

12q13.13  [51,984,050  -  52,202,297]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7670495
9295353
9828131
10066808
10779552
14702039
15282281
15302875
15676283
16014723
16382098
16702217
16775201
17805013
17881658
18718804
18812204
19136557
19352218
20204400
20351042
20379614
20421839
20483028
20530479
20600647
20632842
21156207
21562192
21630263
22365152
23640885

Gene Ontology  (GO ID)

Biological Process

GO:0007628  adult walking behavior
GO:0007411  axon guidance
GO:0007517  muscle organ development
GO:0042552  myelination
GO:0007399  nervous system development
GO:0050905  neuromuscular process
GO:0007422  peripheral nervous system development
GO:0009636  response to toxin
GO:0007605  sensory perception of sound
GO:0006814  sodium ion transport

Cellular Component

GO:0043025  cell soma
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0030425  dendrite
GO:0043194  initial segment
GO:0016021  integral to membrane
GO:0033268  node of Ranvier
GO:0001518  voltage-gated sodium channel complex
GO:0030018  Z disc

Molecular Function

GO:0005524  ATP binding
GO:0005248  voltage-gated sodium channel activity