solute carrier family 4, anion exchanger, member 3

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Synonym

solute carrier family 4, anion exchanger, member 3, Anion exchange protein 3, Neuronal band 3-like protein, SLC2C, AE3, CAE3/BAE3, Cardiac/brain band 3-like protein, Solute carrier family 4 member 3, SLC4A3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:88.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.83 cerebellum:6.54 brain stem:6.88 corpus callosum/glia:5.58 pineal gland:- peripheral nerve:6.05 spine:6.03 retina:- eye:- artery/aorta:6.10 vein:5.92 lymphnode:5.05 peripheral blood:- spleen:5.08 thymus:5.19 bone marrow:5.45 adipose:5.30 bone:- skin:5.39
CAGE cerebrum:3.44 cerebellum:- brain stem:2.87 corpus callosum/glia:2.43 pineal gland:3.98 peripheral nerve:- spine:2.10 retina:- eye:- artery/aorta:1.28 vein:1.49 lymphnode:0.31 peripheral blood:- spleen:0.71 thymus:0.46 bone marrow:- adipose:0.55 bone:- skin:-
RNA-seq cerebrum:2.58 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.38 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.15 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.30 placenta:5.11 prostate:5.38 ovary:6.17 testis:5.91 heart:7.82 muscle:5.34 esophagus:5.19 stomach:4.90 intestine:5.04 colon:5.06 liver/hepato:4.84 lung:5.12 bladder:- kidney:5.29 pituitary:7 thyroid/parathyroid:5.21 adrenal gland:6.23 pancreas:5.02 breast:5.43 salivary:5.44
CAGE uterus:2.02 placenta:1.39 prostate:2.00 ovary:3.18 testis:2.06 heart:4.53 muscle:0.30 esophagus:1.85 stomach:- intestine:0.53 colon:0.46     liver/hepato:0    lung:0.48 bladder:1.06 kidney:1.17 pituitary:3.31 thyroid/parathyroid:0.49 adrenal gland:- pancreas:0.58 breast:0 salivary:1.49
RNA-seq uterus:- placenta:- prostate:1.33 ovary:3.97 testis:2.24 heart:5.28 muscle:0.03 esophagus:- stomach:- intestine:- colon:0.73     liver/hepato:0.02        lung:0.34    bladder:- kidney:1.03 pituitary:- thyroid/parathyroid:0.61 adrenal gland:0.22 pancreas:- breast:0.42 salivary:-

Gene Information

IDs

Refseq ID NM_005070
Gene ID 6508
Unigene ID Hs.117694
Probe set ID 205918_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000114923
GTEx ID ENSG00000114923

Orthologous Gene

Mouse[2]  NM_009208
Rat [0]  

Chromosomal Region

2q35  [220,492,049  -  220,506,702]

Gene Family (Interpro ID)

IPR001717  Anion exchange protein
IPR002979  Anion exchange protein 3
IPR003020  Bicarbonate transporter, eukaryotic

Link to Pubmed  (Pubmed ID)

2686841
7923606
8001971
8227202
10362722
10732805
11208611
11248201
11606574
11739292
11842009
11875255
11875273
11994299
12027221
12477932
19605733
19854014
21139048

Gene Ontology  (GO ID)

Biological Process

GO:0015701  bicarbonate transport
GO:0006811  ion transport
GO:0051453  regulation of intracellular pH
GO:0055085  transmembrane transport
GO:0006810  transport

Cellular Component

GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005452  inorganic anion exchanger activity