neutrophil cytosolic factor 1

Synonym

Neutrophil NADPH oxidase factor 1, 47 kDa neutrophil oxidase factor, Neutrophil cytosol factor 1, NCF-47K, NCF-1, NCF1, chronic granulomatous disease, NOXO2, p47-phox, p47phox, NCF1A, SH3PXD1A

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:4.61

cerebellum:4.55

brain stem:4.74

corpus callosum/glia:4.84

pineal gland:-

peripheral nerve:4.47

spine:4.67

retina:-

eye:-

artery/aorta:4.96

vein:4.88

lymphnode:7.06

peripheral blood:-

spleen:7.57

thymus:5.66

bone marrow:7.63

adipose:5.27

bone:-

skin:5.12

CAGE

nodata

RNA-seq

cerebrum:0.39

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.67

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.52

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:4.68

placenta:4.61

prostate:4.53

ovary:4.75

testis:4.54

heart:4.81

muscle:4.93

esophagus:4.92

stomach:4.98

intestine:5.14

colon:5.20

liver/hepato:4.65

lung:5.51

bladder:-

kidney:4.48

pituitary:4.40

thyroid/parathyroid:4.70

adrenal gland:4.64

pancreas:4.73

breast:4.70

salivary:4.88

CAGE

nodata

RNA-seq

uterus:-

placenta:-

prostate:0.99

ovary:0.76

testis:0.47

heart:0.49

muscle:0.21

esophagus:-

stomach:-

intestine:-

colon:0.45

liver/hepato:0.52

lung:1.47

bladder:-

kidney:0.47

pituitary:-

thyroid/parathyroid:0.81

adrenal gland:4.01

pancreas:-

breast:1.41

salivary:-

IDs

Refseq ID	NM_000265
Gene ID	653361
Unigene ID	Hs.647047
Probe set ID	214084_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000158517
GTEx ID	ENSG00000158517

Orthologous Gene

Mouse[2]	NM_010876
Rat[1]	NM_053734

Chromosomal Region

7q11.23 [74,188,309 - 74,203,659]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
GO:0007154	cell communication
GO:0008283	cell proliferation
GO:0006968	cellular defense response
GO:0006184	GTP catabolic process
GO:0050665	hydrogen peroxide biosynthetic process
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0051701	interaction with host
GO:0006691	leukotriene metabolic process
GO:0045986	negative regulation of smooth muscle contraction
GO:0070947	neutrophil mediated killing of fungus
GO:0070946	neutrophil mediated killing of gram-positive bacterium
GO:0006612	protein targeting to membrane
GO:0045730	respiratory burst
GO:0002679	respiratory burst during defense response
GO:0001878	response to yeast
GO:0042554	superoxide anion generation
GO:0006801	superoxide metabolic process

Cellular Component

GO:0005829	cytosol
GO:0043020	NADPH oxidase complex
GO:0032010	phagolysosome

Molecular Function

GO:0009055	electron carrier activity
GO:0005525	GTP binding
GO:0003924	GTPase activity
GO:0035091	phosphoinositide binding
GO:0005515	protein binding
GO:0017124	SH3 domain binding
GO:0016175	superoxide-generating NADPH oxidase activity

neutrophil cytosolic factor 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function