solute carrier family 8 (sodium/calcium exchanger), member 1

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Synonym

Na(+)/Ca(2+)-exchange protein 1, DKFZp779F0871, Sodium/calcium exchanger 1 precursor, SLC8A1, NCX1, MGC119581

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:69.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:17.60 artery/aorta:- vein:- lymphnode:20.20 peripheral blood:18.20 spleen:18.90 thymus:12.90 bone marrow:78.70 adipose:- bone:- skin:57.60
GeneChip cerebrum:3.24 cerebellum:3.05 brain stem:3.26 corpus callosum/glia:3.05 pineal gland:- peripheral nerve:3.09 spine:3.05 retina:- eye:- artery/aorta:3.13 vein:3.26 lymphnode:3.06 peripheral blood:- spleen:3.09 thymus:2.95 bone marrow:3.17 adipose:3.11 bone:- skin:3.16
CAGE cerebrum:3.65 cerebellum:- brain stem:2.97 corpus callosum/glia:2.69 pineal gland:5.36 peripheral nerve:- spine:2.99 retina:- eye:- artery/aorta:2.93 vein:2.52 lymphnode:2.23 peripheral blood:- spleen:2.99 thymus:1.71 bone marrow:- adipose:2.50 bone:- skin:-
RNA-seq cerebrum:0.56 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.52 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.86 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:21.90 prostate:67.60 ovary:37.30 testis:4.30 heart:395.90 muscle:20.10 esophagus:- stomach:85 intestine:32.40 colon:50.90     liver/hepato:52.80        lung:34.20    bladder:- kidney:52 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:124.50 breast:46.50 salivary:-
GeneChip uterus:3.41 placenta:3.35 prostate:3.25 ovary:3.28 testis:2.98 heart:3.93 muscle:3.27 esophagus:3.13 stomach:3.05 intestine:3.10 colon:3.28 liver/hepato:2.97 lung:3.01 bladder:- kidney:3.10 pituitary:3.12 thyroid/parathyroid:3.05 adrenal gland:3.05 pancreas:2.87 breast:3.07 salivary:2.97
CAGE uterus:3.83 placenta:2.40 prostate:3.69 ovary:2.84 testis:1.89 heart:5.10 muscle:0.87 esophagus:2.62 stomach:- intestine:3.01 colon:3.05     liver/hepato:1.69    lung:2.73 bladder:4.09 kidney:3.78 pituitary:2.47 thyroid/parathyroid:1.07 adrenal gland:- pancreas:1.21 breast:2.11 salivary:1.75
RNA-seq uterus:- placenta:- prostate:1.57 ovary:0.99 testis:1.30 heart:0 muscle:0.55 esophagus:- stomach:- intestine:- colon:0.71     liver/hepato:0.00        lung:0.46    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.62 adrenal gland:1.64 pancreas:- breast:0.95 salivary:-

Gene Ontology  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0055074  calcium ion homeostasis
GO:0070509  calcium ion import
GO:0060402  calcium ion transport into cytosol
GO:0055013  cardiac muscle cell development
GO:0060048  cardiac muscle contraction
GO:0071313  cellular response to caffeine
GO:0071320  cellular response to cAMP
GO:0034614  cellular response to reactive oxygen species
GO:0060401  cytosolic calcium ion transport
GO:0035050  embryonic heart tube development
GO:0001892  embryonic placenta development
GO:0003007  heart morphogenesis
GO:0006811  ion transport
GO:0006936  muscle contraction
GO:0048747  muscle fiber development
GO:0010763  positive regulation of fibroblast migration
GO:0009791  post-embryonic development
GO:0051481  reduction of cytosolic calcium ion concentration
GO:0010881  regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0002027  regulation of heart rate
GO:0002028  regulation of sodium ion transport
GO:0002026  regulation of the force of heart contraction
GO:0055119  relaxation of cardiac muscle
GO:0033198  response to ATP
GO:0042493  response to drug
GO:0009749  response to glucose stimulus
GO:0042542  response to hydrogen peroxide
GO:0001666  response to hypoxia
GO:0007584  response to nutrient
GO:0071436  sodium ion export
GO:0021537  telencephalon development
GO:0055085  transmembrane transport
GO:0014829  vascular smooth muscle contraction

Cellular Component

GO:0016323  basolateral plasma membrane
GO:0043197  dendritic spine
GO:0005887  integral to plasma membrane
GO:0014704  intercalated disc
GO:0005874  microtubule
GO:0005739  mitochondrion
GO:0005886  plasma membrane
GO:0042383  sarcolemma
GO:0030315  T-tubule
GO:0030018  Z disc

Molecular Function

GO:0030506  ankyrin binding
GO:0005432  calcium:sodium antiporter activity
GO:0005516  calmodulin binding
GO:0008092  cytoskeletal protein binding
GO:0046872  metal ion binding