SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1

 jump to detail

Synonym

CRACD1, SWI/SNF complex 60 kDa subunit, 60 kDa BRG-1/Brm-associated factor subunit A, SMARCD1, BRG1-associated factor 60A, BAF60A

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:40.30 cerebellum:63 brain stem:- corpus callosum/glia:- pineal gland:296.70 peripheral nerve:61.30 spine:112.30 retina:- eye:58.80 artery/aorta:30 vein:- lymphnode:40.40 peripheral blood:36.40 spleen:18.90 thymus:141.70 bone marrow:39.40 adipose:40.30 bone:64 skin:24
GeneChip cerebrum:5.18 cerebellum:5.34 brain stem:5.22 corpus callosum/glia:5.21 pineal gland:- peripheral nerve:5.23 spine:5.14 retina:- eye:- artery/aorta:5.17 vein:5.20 lymphnode:5.13 peripheral blood:- spleen:5.03 thymus:5.12 bone marrow:5.06 adipose:5.40 bone:- skin:5.16
CAGE cerebrum:3.40 cerebellum:- brain stem:3.20 corpus callosum/glia:3.80 pineal gland:3.36 peripheral nerve:- spine:3.43 retina:- eye:- artery/aorta:3.37 vein:3.75 lymphnode:3.51 peripheral blood:- spleen:3.72 thymus:4.36 bone marrow:- adipose:3.45 bone:- skin:-
RNA-seq cerebrum:0.09 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.48 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.21 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:21.90 prostate:11.30 ovary:37.30 testis:43.30 heart:51.10 muscle:- esophagus:- stomach:- intestine:64.80 colon:25.40     liver/hepato:-        lung:24.40    bladder:- kidney:52 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:53.30 breast:46.50 salivary:-
GeneChip uterus:5.06 placenta:5.12 prostate:4.62 ovary:5 testis:5.04 heart:5.08 muscle:5.16 esophagus:5.09 stomach:4.86 intestine:4.98 colon:5.19 liver/hepato:5.07 lung:5.17 bladder:- kidney:5.12 pituitary:5.17 thyroid/parathyroid:4.96 adrenal gland:5.01 pancreas:4.75 breast:5.14 salivary:5.10
CAGE uterus:3.44 placenta:3.50 prostate:3.28 ovary:3.55 testis:3.87 heart:3.19 muscle:3.13 esophagus:3.26 stomach:- intestine:3.54 colon:3.41     liver/hepato:3.13    lung:3.33 bladder:3.10 kidney:3.57 pituitary:3.05 thyroid/parathyroid:3.48 adrenal gland:- pancreas:3.16 breast:3.27 salivary:3.24
RNA-seq uterus:- placenta:- prostate:0.52 ovary:0.71 testis:0.82 heart:0.09 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.86     liver/hepato:0.00        lung:1.52    bladder:- kidney:0.42 pituitary:- thyroid/parathyroid:0.09 adrenal gland:0.00 pancreas:- breast:0.21 salivary:-

Gene Information

IDs

Refseq ID NM_139071
Gene ID 6602
Unigene ID Hs.79335
Probe set ID 203183_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000066117
GTEx ID ENSG00000066117

Orthologous Gene

Mouse[1]  NM_031842
Rat[1]  NM_001108752

Chromosomal Region

12q13.12  [50,478,755  -  50,494,495]

Gene Family (Interpro ID)

IPR019835  SWIB domain
IPR003121  SWIB/MDM2 domain

Link to Pubmed  (Pubmed ID)

8804307
8889549
8895581
9693044
9710619
9892636
10078207
11018012
11053448
11078522
11726552
11734557
11784859
12477932
12665591
12753905
12917342
14559996
14729568
15146197
15489334
15985610
16189514
16199878
16344560
16484223
17474147
18029348
18042045
18303029
18809673
19371634
19454010
19762545
20211142
20305087
20360068
20460684
21118156
21532573
21890473
21906983
21963094
21988832
22285184
22334708
22505724
22678362
22939629
22990118
23000965
23455924
24255178
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006338  chromatin remodeling
GO:0048096  chromatin-mediated maintenance of transcription
GO:0007399  nervous system development
GO:0006337  nucleosome disassembly
GO:0006357  regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0016514  SWI/SNF complex

Molecular Function

GO:0005515  protein binding
GO:0032947  protein complex scaffold
GO:0003713  transcription coactivator activity