SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3

 jump to detail

Synonym

SMARCD3, CRACD3, BRG1-associated factor 60C, MGC111010, BAF60C, 60 kDa BRG-1/Brm-associated factor subunit C

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:7.31 cerebellum:7.05 brain stem:7.17 corpus callosum/glia:6.35 pineal gland:- peripheral nerve:6.42 spine:6.69 retina:- eye:- artery/aorta:7.24 vein:7.02 lymphnode:5.76 peripheral blood:- spleen:5.08 thymus:4.56 bone marrow:5.19 adipose:6.09 bone:- skin:6.03
CAGE cerebrum:4.07 cerebellum:- brain stem:3.75 corpus callosum/glia:3.41 pineal gland:3.02 peripheral nerve:- spine:3.89 retina:- eye:- artery/aorta:4.12 vein:2.60 lymphnode:2.40 peripheral blood:- spleen:2.20 thymus:0.88 bone marrow:- adipose:2.57 bone:- skin:-
RNA-seq cerebrum:3.32 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.06 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.38 placenta:4.56 prostate:6.12 ovary:6.93 testis:6.43 heart:7.30 muscle:7.80 esophagus:6 stomach:5.68 intestine:6.23 colon:5.58 liver/hepato:4.43 lung:5.85 bladder:- kidney:5.62 pituitary:6.98 thyroid/parathyroid:6.50 adrenal gland:7.32 pancreas:5.52 breast:6.19 salivary:5.53
CAGE uterus:3.20 placenta:1.59 prostate:3.39 ovary:3.95 testis:3.12 heart:3.70 muscle:4.84 esophagus:2.96 stomach:- intestine:2.04 colon:2.66     liver/hepato:0.55    lung:2.98 bladder:3.18 kidney:2.77 pituitary:3.74 thyroid/parathyroid:2.95 adrenal gland:- pancreas:3.29 breast:3.49 salivary:2.60
RNA-seq uterus:- placenta:- prostate:3.36 ovary:5.15 testis:4.85 heart:3.70 muscle:4.64 esophagus:- stomach:- intestine:- colon:3.40     liver/hepato:0.62        lung:2.44    bladder:- kidney:3.22 pituitary:- thyroid/parathyroid:3.50 adrenal gland:3.46 pancreas:- breast:3.36 salivary:-

Gene Information

IDs

Refseq ID NM_001003801
Gene ID 6604
Unigene ID Hs.647067
Probe set ID 204099_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000082014
GTEx ID ENSG00000082014

Orthologous Gene

Mouse[1]  NM_025891
Rat[1]  NM_001011966

Chromosomal Region

7q36.1  [150,935,850  -  150,974,982]

Gene Family (Interpro ID)

IPR019835  SWIB domain
IPR003121  SWIB/MDM2 domain

Link to Pubmed  (Pubmed ID)

8804307
8895581
9693044
9891079
11726552
12477932
12690205
12853948
14697242
14701856
15489334
16687403
17081983
17363140
17474147
18816825
20305087
21694703
21906983
22068056
22505724
22833560
22939629
23219531
23382691
23563706
23716599
24250222
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0003219  cardiac right ventricle formation
GO:0044255  cellular lipid metabolic process
GO:0006338  chromatin remodeling
GO:0042692  muscle cell differentiation
GO:0003407  neural retina development
GO:0006337  nucleosome disassembly
GO:0002052  positive regulation of neuroblast proliferation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0043393  regulation of protein binding
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0003139  secondary heart field specification
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0000790  nuclear chromatin
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0016514  SWI/SNF complex

Molecular Function

GO:0016922  ligand-dependent nuclear receptor binding
GO:0030374  ligand-dependent nuclear receptor transcription coactivator activity
GO:0035257  nuclear hormone receptor binding
GO:0005515  protein binding
GO:0005102  receptor binding
GO:0003713  transcription coactivator activity
GO:0008134  transcription factor binding