signal transducer and activator of transcription 5B

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Synonym

STAT5B, Stat 5B, STAT 5b, STAT 5B, STAT-5B, Stat 5b, Stat-5B, Stat-5b, STAT-5b, STAT5b, STAT5

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:4.88

cerebellum:5.19

brain stem:5.03

corpus callosum/glia:4.84

pineal gland:-

peripheral nerve:5.13

spine:4.97

retina:-

eye:-

artery/aorta:5.39

vein:5.18

lymphnode:5.29

peripheral blood:-

spleen:5.43

thymus:6

bone marrow:5.72

adipose:5.56

bone:-

skin:5.32

CAGE

cerebrum:3.04

cerebellum:-

brain stem:3.16

corpus callosum/glia:3.12

pineal gland:3.43

peripheral nerve:-

spine:2.98

retina:-

eye:-

artery/aorta:3.56

vein:3.24

lymphnode:3.54

peripheral blood:-

spleen:3.22

thymus:3.36

bone marrow:-

adipose:3.53

bone:-

skin:-

RNA-seq

cerebrum:3.42

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.81

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.80

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:5.57

placenta:6.63

prostate:5.67

ovary:5.52

testis:4.95

heart:4.78

muscle:5.66

esophagus:4.88

stomach:4.94

intestine:5.08

colon:5.11

liver/hepato:4.90

lung:5.10

bladder:-

kidney:4.92

pituitary:5.65

thyroid/parathyroid:5.11

adrenal gland:5.17

pancreas:5.30

breast:5.17

salivary:4.91

CAGE

uterus:3.64

placenta:4.38

prostate:3.54

ovary:3.65

testis:2.89

heart:3.11

muscle:3.59

esophagus:2.89

stomach:-

intestine:2.82

colon:3.27

liver/hepato:2.86

lung:3.14

bladder:3.51

kidney:2.80

pituitary:3.41

thyroid/parathyroid:3.11

adrenal gland:-

pancreas:2.90

breast:3.75

salivary:2.93

RNA-seq

uterus:-

placenta:-

prostate:5.03

ovary:4.99

testis:4.69

heart:2.93

muscle:5.28

esophagus:-

stomach:-

intestine:-

colon:4.70

liver/hepato:2.87

lung:4.83

bladder:-

kidney:3.71

pituitary:-

thyroid/parathyroid:4.27

adrenal gland:4.58

pancreas:-

breast:5.05

salivary:-

IDs

Refseq ID	NM_012448
Gene ID	6777
Unigene ID	-
Probe set ID	212550_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000173757
GTEx ID	ENSG00000173757

Orthologous Gene

Mouse[4]	NM_001113563, NM_011489
Rat [0]

Chromosomal Region

17q21.2 [40,351,186 - 40,428,725]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0006103	2-oxoglutarate metabolic process
GO:0006953	acute-phase response
GO:0000255	allantoin metabolic process
GO:0032870	cellular response to hormone stimulus
GO:0006101	citrate metabolic process
GO:0006600	creatine metabolic process
GO:0046449	creatinine metabolic process
GO:0046543	development of secondary female sexual characteristics
GO:0046544	development of secondary male sexual characteristics
GO:0006631	fatty acid metabolic process
GO:0007565	female pregnancy
GO:0006549	isoleucine metabolic process
GO:0007259	JAK-STAT cascade
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway
GO:0007595	lactation
GO:0019915	lipid storage
GO:0001889	liver development
GO:0001553	luteinization
GO:0001779	natural killer cell differentiation
GO:0043066	negative regulation of apoptosis
GO:0045647	negative regulation of erythrocyte differentiation
GO:0006107	oxaloacetate metabolic process
GO:0048541	Peyer's patch development
GO:0042104	positive regulation of activated T cell proliferation
GO:0045579	positive regulation of B cell differentiation
GO:0051272	positive regulation of cellular component movement
GO:0045588	positive regulation of gamma-delta T cell differentiation
GO:0050729	positive regulation of inflammatory response
GO:0045086	positive regulation of interleukin-2 biosynthetic process
GO:0045931	positive regulation of mitotic cell cycle
GO:0040018	positive regulation of multicellular organism growth
GO:0032825	positive regulation of natural killer cell differentiation
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity
GO:0032819	positive regulation of natural killer cell proliferation
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0042448	progesterone metabolic process
GO:0030155	regulation of cell adhesion
GO:0030856	regulation of epithelial cell differentiation
GO:0040014	regulation of multicellular organism growth
GO:0019218	regulation of steroid metabolic process
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0032355	response to estradiol stimulus
GO:0045471	response to ethanol
GO:0001666	response to hypoxia
GO:0070672	response to interleukin-15
GO:0070669	response to interleukin-2
GO:0070670	response to interleukin-4
GO:0032496	response to lipopolysaccharide
GO:0006105	succinate metabolic process
GO:0033077	T cell differentiation in the thymus
GO:0043029	T cell homeostasis
GO:0019530	taurine metabolic process
GO:0006366	transcription from RNA polymerase II promoter
GO:0006573	valine metabolic process

Cellular Component

GO:0005829	cytosol
GO:0005654	nucleoplasm

Molecular Function

GO:0005509	calcium ion binding
GO:0003690	double-stranded DNA binding
GO:0035259	glucocorticoid receptor binding
GO:0005515	protein binding
GO:0004871	signal transducer activity
GO:0003700	transcription factor activity

signal transducer and activator of transcription 5B

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function