transcription factor 15 (basic helix-loop-helix)

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Synonym

transcription factor 15 (basic helix-loop-helix), Transcription factor 15, BHLHEC2, bHLH-EC2 protein, EC2, TCF15, Paraxis, PARAXIS

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.31 cerebellum:6.73 brain stem:6.39 corpus callosum/glia:6.47 pineal gland:- peripheral nerve:5.64 spine:5.88 retina:- eye:- artery/aorta:5.94 vein:6.81 lymphnode:6 peripheral blood:- spleen:5.65 thymus:5.30 bone marrow:6.14 adipose:6.23 bone:- skin:5.98
CAGE cerebrum:0.24 cerebellum:- brain stem:0.26 corpus callosum/glia:0.07 pineal gland:0.21 peripheral nerve:- spine:0.23 retina:- eye:- artery/aorta:0.59 vein:1.17 lymphnode:0 peripheral blood:- spleen:0 thymus:0.23 bone marrow:- adipose:1.29 bone:- skin:-
RNA-seq cerebrum:0.08 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.97 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.60 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:11.30 ovary:- testis:77.90 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:24.40    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.11 placenta:6.13 prostate:5.34 ovary:6.24 testis:5.69 heart:6.79 muscle:6.78 esophagus:6.28 stomach:6.28 intestine:6.39 colon:6.57 liver/hepato:6.24 lung:6.32 bladder:- kidney:6.26 pituitary:6 thyroid/parathyroid:5.54 adrenal gland:6.30 pancreas:6.72 breast:5.97 salivary:6.30
CAGE uterus:0.40 placenta:1.82 prostate:0.53 ovary:0.14 testis:0.62 heart:2.46 muscle:1.58 esophagus:0.90 stomach:- intestine:0 colon:0.29     liver/hepato:0.14    lung:0.42 bladder:0.18 kidney:0.08 pituitary:0 thyroid/parathyroid:0.49 adrenal gland:- pancreas:0 breast:1.92 salivary:0.36
RNA-seq uterus:- placenta:- prostate:0.85 ovary:0.11 testis:0.83 heart:2.61 muscle:1.31 esophagus:- stomach:- intestine:- colon:0.76     liver/hepato:0.02        lung:1.11    bladder:- kidney:0.21 pituitary:- thyroid/parathyroid:0.40 adrenal gland:0.36 pancreas:- breast:1.39 salivary:-

Gene Information

IDs

Refseq ID NM_004609
Gene ID 6939
Unigene ID Hs.437006
Probe set ID 207306_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000125878
GTEx ID ENSG00000125878

Orthologous Gene

Mouse[1]  NM_009328
Rat [0]  

Chromosomal Region

20p13  [584,441  -  591,042]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8041747
8825648
11780052
12477932
19419955
22145905

Gene Ontology  (GO ID)

Biological Process

GO:0016265  death
GO:0043583  ear development
GO:0042755  eating behavior
GO:0007498  mesoderm development
GO:0048644  muscle organ morphogenesis
GO:0050884  neuromuscular process controlling posture
GO:0048339  paraxial mesoderm development
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0003016  respiratory system process
GO:0048705  skeletal system morphogenesis
GO:0043588  skin development
GO:0001756  somitogenesis
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0046983  protein dimerization activity
GO:0003700  transcription factor activity