thymidine kinase 2, mitochondrial

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Synonym

Thymidine kinase 2, mitochondrial precursor, thymidine kinase 2, mitochondrial, TK2, Mt-TK

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:69.90 cerebellum:25.20 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:92 spine:224.60 retina:118.60 eye:5.90 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:18.20 spleen:- thymus:25.80 bone marrow:- adipose:40.30 bone:38.40 skin:28.80
GeneChip cerebrum:6.63 cerebellum:5.91 brain stem:6.64 corpus callosum/glia:6.62 pineal gland:- peripheral nerve:6.92 spine:6.83 retina:- eye:- artery/aorta:6.82 vein:6.32 lymphnode:6.33 peripheral blood:- spleen:6.40 thymus:5.94 bone marrow:5.60 adipose:7.24 bone:- skin:6.45
CAGE cerebrum:3.66 cerebellum:- brain stem:3.59 corpus callosum/glia:3.52 pineal gland:3.57 peripheral nerve:- spine:3.99 retina:- eye:- artery/aorta:3.96 vein:3.61 lymphnode:2.82 peripheral blood:- spleen:2.95 thymus:2.16 bone marrow:- adipose:4.00 bone:- skin:-
RNA-seq cerebrum:0.71 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.54 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.70 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:32.80 prostate:45.10 ovary:- testis:77.90 heart:51.10 muscle:20.10 esophagus:- stomach:21.20 intestine:- colon:17     liver/hepato:-        lung:24.40    bladder:- kidney:52 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:27.90 salivary:-
GeneChip uterus:6.30 placenta:5.99 prostate:6.50 ovary:6.56 testis:7.17 heart:6.31 muscle:5.80 esophagus:6.16 stomach:6.26 intestine:6.11 colon:5.84 liver/hepato:6.85 lung:6.57 bladder:- kidney:6.73 pituitary:6.75 thyroid/parathyroid:7.06 adrenal gland:7.38 pancreas:6.32 breast:6.78 salivary:6.95
CAGE uterus:3.35 placenta:2.83 prostate:2.99 ovary:3.24 testis:3.67 heart:3.37 muscle:3.18 esophagus:2.87 stomach:- intestine:2.75 colon:3.09     liver/hepato:3.66    lung:3.40 bladder:2.92 kidney:3.24 pituitary:3.13 thyroid/parathyroid:2.93 adrenal gland:- pancreas:3.67 breast:3.93 salivary:3.63
RNA-seq uterus:- placenta:- prostate:1.53 ovary:0.57 testis:0.17 heart:0.99 muscle:0.82 esophagus:- stomach:- intestine:- colon:0.28     liver/hepato:1.52        lung:0.75    bladder:- kidney:0.85 pituitary:- thyroid/parathyroid:0.49 adrenal gland:0.46 pancreas:- breast:1.34 salivary:-

Gene Information

IDs

Refseq ID NM_004614
Gene ID 7084
Unigene ID Hs.512619
Probe set ID 204276_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000166548
GTEx ID ENSG00000166548

Orthologous Gene

Mouse[1]  NM_021028
Rat[1]  NM_001106166

Chromosomal Region

16q21  [66,541,906  -  66,584,315]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

605384
1597187
9079672
9598140
9989599
11687801
12391347
12477932
12493767
12682338
12687391
12873860
14659972
15639197
15907288
16344560
16969512
17065084
17468435
17913703
18021809
18265975
18446447
18508266
19154348
19265691
19736010
19878914
20237496
20877624
21382338
21937588
22661713
23230576
23932787
24198295

Gene Ontology  (GO ID)

Biological Process

GO:0046092  deoxycytidine metabolic process
GO:0009262  deoxyribonucleotide metabolic process
GO:0006264  mitochondrial DNA replication
GO:0055086  nucleobase, nucleoside and nucleotide metabolic process
GO:0006139  nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0006206  pyrimidine base metabolic process
GO:0043097  pyrimidine nucleoside salvage
GO:0046104  thymidine metabolic process

Cellular Component

GO:0005743  mitochondrial inner membrane
GO:0005759  mitochondrial matrix

Molecular Function

GO:0005524  ATP binding
GO:0004137  deoxycytidine kinase activity
GO:0016773  phosphotransferase activity, alcohol group as acceptor
GO:0004797  thymidine kinase activity