toll-like receptor 1

Synonym

KIAA0012, MGC126312, MGC104956, DKFZp547I0610, TLR1, Toll/interleukin-1 receptor-like protein, rsc786, DKFZp564I0682, toll-like receptor 1, TIL, MGC126311, Toll-like receptor 1 precursor, CD281, CD281 antigen

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:3.27

cerebellum:3.09

brain stem:3.37

corpus callosum/glia:3.74

pineal gland:-

peripheral nerve:3.84

spine:3.76

retina:-

eye:-

artery/aorta:3.29

vein:3.22

lymphnode:4.49

peripheral blood:-

spleen:4.79

thymus:4.10

bone marrow:4.95

adipose:3.65

bone:-

skin:3.64

CAGE

cerebrum:1.91

cerebellum:-

brain stem:2.55

corpus callosum/glia:2.35

pineal gland:1.95

peripheral nerve:-

spine:3.13

retina:-

eye:-

artery/aorta:1.88

vein:2.47

lymphnode:3.23

peripheral blood:-

spleen:4.16

thymus:2.75

bone marrow:-

adipose:3.07

bone:-

skin:-

RNA-seq

cerebrum:1.93

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.86

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.52

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:3.54

placenta:3.49

prostate:3.29

ovary:4.03

testis:2.84

heart:3.49

muscle:3.24

esophagus:3.23

stomach:3.41

intestine:3.67

colon:3.23

liver/hepato:3.61

lung:3.93

bladder:-

kidney:3.33

pituitary:3.29

thyroid/parathyroid:3.13

adrenal gland:3.16

pancreas:3.66

breast:3.55

salivary:3.80

CAGE

uterus:1.91

placenta:2.42

prostate:2.20

ovary:2.13

testis:1.07

heart:1.60

muscle:0.99

esophagus:1.89

stomach:-

intestine:2.27

colon:0.85

liver/hepato:2.25

lung:2.93

bladder:1.81

kidney:2.28

pituitary:2.07

thyroid/parathyroid:1.40

adrenal gland:-

pancreas:1.59

breast:1.36

salivary:1.82

RNA-seq

uterus:-

placenta:-

prostate:1.35

ovary:1.42

testis:0.79

heart:0.78

muscle:0.12

esophagus:-

stomach:-

intestine:-

colon:0.52

liver/hepato:1.56

lung:1.93

bladder:-

kidney:1.67

pituitary:-

thyroid/parathyroid:0.81

adrenal gland:2.53

pancreas:-

breast:1.51

salivary:-

IDs

Refseq ID	NM_003263
Gene ID	7096
Unigene ID	-
Probe set ID	210176_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000174125
GTEx ID	ENSG00000174125

Orthologous Gene

Mouse[1]	NM_030682
Rat [0]

Chromosomal Region

4p14 [38,792,298 - 38,858,438]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR004075	Interleukin-1 receptor, type I/Toll precursor
IPR000157	Toll-Interleukin receptor

Gene Ontology (GO ID)

Biological Process

GO:0042495	detection of triacylated bacterial lipoprotein
GO:0006955	immune response
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0042116	macrophage activation
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0045410	positive regulation of interleukin-6 biosynthetic process
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
GO:0050707	regulation of cytokine secretion
GO:0007165	signal transduction
GO:0034130	toll-like receptor 1 signaling pathway

Cellular Component

GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0030670	phagocytic vesicle membrane
GO:0005886	plasma membrane

Molecular Function

GO:0046982	protein heterodimerization activity
GO:0004872	receptor activity
GO:0004888	transmembrane receptor activity

toll-like receptor 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function