transient receptor potential cation channel, subfamily C, member 4

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Synonym

hTrp4, MGC119570, TRPC4, MGC119571, MGC119572, hTrp-4, Short transient receptor potential channel 4, HTRP4, MGC119573, TRP4, trp-related protein 4, TrpC4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:19 cerebellum:- brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:5.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.14 cerebellum:4.98 brain stem:5.07 corpus callosum/glia:5.15 pineal gland:- peripheral nerve:4.81 spine:4.77 retina:- eye:- artery/aorta:5 vein:5.87 lymphnode:4.96 peripheral blood:- spleen:4.65 thymus:4.60 bone marrow:5.04 adipose:4.98 bone:- skin:5
CAGE cerebrum:1.40 cerebellum:- brain stem:1.16 corpus callosum/glia:0.79 pineal gland:1.59 peripheral nerve:- spine:1.45 retina:- eye:- artery/aorta:1.33 vein:0.18 lymphnode:0.23 peripheral blood:- spleen:0.09 thymus:0 bone marrow:- adipose:0.84 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:154.90 placenta:3.60 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:10.60        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.36 placenta:4.93 prostate:5.09 ovary:5.18 testis:4.67 heart:5.30 muscle:5.31 esophagus:4.97 stomach:5.15 intestine:5.19 colon:5.22 liver/hepato:4.95 lung:4.95 bladder:- kidney:5.08 pituitary:4.81 thyroid/parathyroid:4.68 adrenal gland:5.06 pancreas:5.85 breast:4.78 salivary:5.15
CAGE uterus:2.95 placenta:1.87 prostate:2.49 ovary:1.43 testis:0.54 heart:0.92 muscle:0.33 esophagus:0.46 stomach:- intestine:0.93 colon:0.40     liver/hepato:0.36    lung:1.41 bladder:1.75 kidney:0.71 pituitary:0.34 thyroid/parathyroid:0.67 adrenal gland:- pancreas:0 breast:0.55 salivary:0
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:0.00 heart:0.00 muscle:0 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_003306
Gene ID 7223
Unigene ID Hs.262960
Probe set ID 220818_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000133107
GTEx ID ENSG00000133107

Orthologous Gene

Mouse[2]  NM_016984
Rat[2]  NM_001083115, NM_080396

Chromosomal Region

13q13.3  [38,210,773  -  38,444,562]

Gene Family (Interpro ID)

IPR004729  Transient receptor potential channel
IPR002153  Transient receptor potential protein

Link to Pubmed  (Pubmed ID)

8646775
10816590
10980202
11042129
11163362
11290752
11713258
11830588
12032305
12154080
12356946
12477932
12736151
12857742
14505576
15146197
15358862
15540229
15757897
16033767
16144838
16254212
16344560
16382100
16527499
17031666
17074721
17081983
17110928
17217052
17920677
18021253
18048348
18976975
19059308
19307462
19725137
19996314
20164195
20379614
20458742
20468064
20574736
21427121
22457348
23251661
23326517
23549783
23677990
24563462

Gene Ontology  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0070509  calcium ion import
GO:0006816  calcium ion transport
GO:0014051  gamma-aminobutyric acid secretion

Cellular Component

GO:0016323  basolateral plasma membrane
GO:0034704  calcium channel complex
GO:0005901  caveola
GO:0009986  cell surface
GO:0005911  cell-cell junction
GO:0030863  cortical cytoskeleton
GO:0005886  plasma membrane

Molecular Function

GO:0008013  beta-catenin binding
GO:0045296  cadherin binding
GO:0070679  inositol 1,4,5 trisphosphate binding
GO:0005515  protein binding
GO:0015279  store-operated calcium channel activity