tocopherol (alpha) transfer protein

 jump to detail

Synonym

alphaTTP, TPP1, TTP1, AVED, Alpha-TTP, Alpha-tocopherol transfer protein, TTPA

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:2.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.53 cerebellum:3.61 brain stem:3.55 corpus callosum/glia:3.55 pineal gland:- peripheral nerve:3.54 spine:3.58 retina:- eye:- artery/aorta:3.48 vein:3.53 lymphnode:3.39 peripheral blood:- spleen:3.50 thymus:3.32 bone marrow:3.71 adipose:3.52 bone:- skin:3.55
CAGE cerebrum:2.00 cerebellum:- brain stem:1.94 corpus callosum/glia:1.96 pineal gland:0.55 peripheral nerve:- spine:2.27 retina:- eye:- artery/aorta:0.34 vein:0.34 lymphnode:0.26 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:1.21 bone:- skin:-
RNA-seq cerebrum:0.81 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.12 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.83 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:10.90 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:32.40 colon:8.50     liver/hepato:-        lung:-    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:18.60 salivary:-
GeneChip uterus:3.39 placenta:3.70 prostate:3.36 ovary:3.40 testis:3.34 heart:3.38 muscle:3.63 esophagus:3.56 stomach:3.47 intestine:3.54 colon:3.68 liver/hepato:6.12 lung:3.49 bladder:- kidney:3.46 pituitary:3.51 thyroid/parathyroid:3.55 adrenal gland:3.45 pancreas:3.71 breast:3.48 salivary:3.65
CAGE uterus:0.10 placenta:0.99 prostate:0.15 ovary:0 testis:0.38 heart:0.35 muscle:0.05 esophagus:0.26 stomach:- intestine:0.27 colon:1.76     liver/hepato:4.83    lung:1.17 bladder:0 kidney:0.62 pituitary:0.10 thyroid/parathyroid:0 adrenal gland:- pancreas:1.21 breast:2.02 salivary:0
RNA-seq uterus:- placenta:- prostate:0.23 ovary:0.04 testis:0.18 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0.36     liver/hepato:5.46        lung:0.22    bladder:- kidney:0.23 pituitary:- thyroid/parathyroid:0.02 adrenal gland:0.06 pancreas:- breast:0.92 salivary:-

Gene Information

IDs

Refseq ID NM_000370
Gene ID 7274
Unigene ID Hs.69049
Probe set ID 210614_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000137561
GTEx ID ENSG00000137561

Orthologous Gene

Mouse[1]  NM_015767
Rat [0]  

Chromosomal Region

8q12.3  [63,961,112  -  63,998,612]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7566022
7719340
7887897
8252047
8602747
8965888
9463307
9931538
12470185
12477932
12899840
14657365
15065857
15190938
15300460
15489334
16226712
16819822
17207965
18458085
18511174
18984846
19102053
19190344
19458973
20301317
20301419
20801516
20826775
21110980
21832049
22752767
23079030
23599266

Gene Ontology  (GO ID)

Biological Process

GO:0001892  embryonic placenta development
GO:0046909  intermembrane transport
GO:0006629  lipid metabolic process
GO:0007584  response to nutrient
GO:0009268  response to pH
GO:0009636  response to toxin
GO:0006810  transport
GO:0042360  vitamin E metabolic process
GO:0051180  vitamin transport

Cellular Component

GO:0005829  cytosol
GO:0005770  late endosome

Molecular Function

GO:0043325  phosphatidylinositol-3,4-bisphosphate binding
GO:0005546  phosphatidylinositol-4,5-bisphosphate binding
GO:0005215  transporter activity
GO:0008431  vitamin E binding