thymidylate synthetase

Synonym

HsT422, Tsase, thymidylate synthetase (TS), TSase, thymidylate synthetase, MGC88736, Thymidylate synthase, TMS, OK/SW-cl.29, TYMS

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:22.50

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:237.30

eye:23.50

artery/aorta:60

vein:-

lymphnode:20.20

peripheral blood:18.20

spleen:37.80

thymus:25.80

bone marrow:39.40

adipose:-

bone:64

skin:43.20

GeneChip

nodata

CAGE

cerebrum:1.32

cerebellum:-

brain stem:1.57

corpus callosum/glia:2.59

pineal gland:0.35

peripheral nerve:-

spine:1.15

retina:-

eye:-

artery/aorta:0.79

vein:2.83

lymphnode:2.18

peripheral blood:-

spleen:2.01

thymus:4.36

bone marrow:-

adipose:1.29

bone:-

skin:-

RNA-seq

nodata

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:94.70

prostate:11.30

ovary:111.80

testis:77.90

heart:25.50

muscle:-

esophagus:-

stomach:63.70

intestine:32.40

colon:25.40

liver/hepato:137.20

lung:19.60

bladder:-

kidney:72.80

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:26.70

breast:18.60

salivary:-

GeneChip

nodata

CAGE

uterus:1.08

placenta:2.74

prostate:1.36

ovary:0.60

testis:2.94

heart:0.83

muscle:0.17

esophagus:1.91

stomach:-

intestine:2.02

colon:2.52

liver/hepato:0.96

lung:1.32

bladder:0.87

kidney:1.50

pituitary:0.19

thyroid/parathyroid:0.28

adrenal gland:-

pancreas:0.58

breast:0.90

salivary:0.62

RNA-seq

nodata

IDs

Refseq ID	NM_001071000
Gene ID	7298
Unigene ID	Hs.592338
Probe set ID	-
Ensembl ID	-
GTEx ID	-

Orthologous Gene

Mouse [0]
Rat [0]

Gene Ontology (GO ID)

Biological Process

GO:0007568	aging
GO:0051216	cartilage development
GO:0007623	circadian rhythm
GO:0009157	deoxyribonucleoside monophosphate biosynthetic process
GO:0048589	developmental growth
GO:0006281	DNA repair
GO:0006260	DNA replication
GO:0006231	dTMP biosynthetic process
GO:0006235	dTTP biosynthetic process
GO:0046078	dUMP metabolic process
GO:0000082	G1/S transition of mitotic cell cycle
GO:0019088	immortalization of host cell by virus
GO:0060574	intestinal epithelial cell maturation
GO:0000278	mitotic cell cycle
GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0031100	organ regeneration
GO:0048015	phosphoinositide-mediated signaling
GO:0005976	polysaccharide metabolic process
GO:0006206	pyrimidine base metabolic process
GO:0046134	pyrimidine nucleoside biosynthetic process
GO:0000083	regulation of transcription involved in G1/S-phase of mitotic cell cycle
GO:0034097	response to cytokine stimulus
GO:0042493	response to drug
GO:0045471	response to ethanol
GO:0051593	response to folic acid
GO:0051384	response to glucocorticoid stimulus
GO:0046683	response to organophosphorus
GO:0032570	response to progesterone stimulus
GO:0009636	response to toxin
GO:0033189	response to vitamin A
GO:0046653	tetrahydrofolate metabolic process
GO:0019860	uracil metabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005743	mitochondrial inner membrane
GO:0005759	mitochondrial matrix
GO:0005739	mitochondrion
GO:0005730	nucleolus
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0048037	cofactor binding
GO:0008144	drug binding
GO:0005542	folic acid binding
GO:0003729	mRNA binding
GO:0000166	nucleotide binding
GO:0042803	protein homodimerization activity
GO:0004799	thymidylate synthase activity

thymidylate synthetase

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function