uridine phosphorylase 1

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Synonym

UPP, uridine phosphorylase 1, UPase 1, UP, uridine phosphorylase, UPASE, UrdPase 1, UDRPASE, UPP1, Uridine phosphorylase 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:8.30 cerebellum:37.80 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:41.10 artery/aorta:- vein:133.30 lymphnode:- peripheral blood:109.30 spleen:37.80 thymus:- bone marrow:118.10 adipose:- bone:25.60 skin:48
GeneChip cerebrum:5.75 cerebellum:6.93 brain stem:5.83 corpus callosum/glia:5.22 pineal gland:- peripheral nerve:5.52 spine:5.57 retina:- eye:- artery/aorta:6.50 vein:6.69 lymphnode:6.21 peripheral blood:- spleen:5.94 thymus:4.62 bone marrow:6.15 adipose:5.95 bone:- skin:5.87
CAGE cerebrum:2.03 cerebellum:- brain stem:2.35 corpus callosum/glia:1.68 pineal gland:2.77 peripheral nerve:- spine:2.48 retina:- eye:- artery/aorta:3.20 vein:2.49 lymphnode:3.59 peripheral blood:- spleen:3.31 thymus:1.31 bone marrow:- adipose:3.55 bone:- skin:-
RNA-seq cerebrum:1.49 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.93 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.23 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:82 placenta:98.40 prostate:78.90 ovary:74.50 testis:8.70 heart:12.80 muscle:- esophagus:- stomach:- intestine:32.40 colon:25.40     liver/hepato:31.70        lung:53.80    bladder:- kidney:52 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:8.90 breast:18.60 salivary:-
GeneChip uterus:5.39 placenta:7.30 prostate:4.83 ovary:4.90 testis:5.15 heart:6.09 muscle:5.29 esophagus:8.45 stomach:5.12 intestine:5.72 colon:5.76 liver/hepato:5.46 lung:7.52 bladder:- kidney:5.76 pituitary:5.72 thyroid/parathyroid:5.60 adrenal gland:6.19 pancreas:5.04 breast:5.34 salivary:4.52
CAGE uterus:2.54 placenta:3.95 prostate:2.02 ovary:2.01 testis:1.51 heart:2.71 muscle:2.31 esophagus:3.66 stomach:- intestine:2.95 colon:2.73     liver/hepato:2.71    lung:3.81 bladder:2.81 kidney:2.82 pituitary:2.25 thyroid/parathyroid:2.53 adrenal gland:- pancreas:2.26 breast:2.79 salivary:1.15
RNA-seq uterus:- placenta:- prostate:2.64 ovary:1.69 testis:1.71 heart:0.99 muscle:0.33 esophagus:- stomach:- intestine:- colon:2.86     liver/hepato:2.53        lung:3.66    bladder:- kidney:3.10 pituitary:- thyroid/parathyroid:1.96 adrenal gland:2.99 pancreas:- breast:1.85 salivary:-

Gene Information

IDs

Refseq ID NM_003364
Gene ID 7378
Unigene ID Hs.488240
Probe set ID 203234_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000183696
GTEx ID ENSG00000183696

Orthologous Gene

Mouse[3]  NM_001159401, NM_001159402, NM_009477
Rat[1]  NM_001030025, NM_001159402, NM_009477

Chromosomal Region

7p12.3  [48,128,225  -  48,148,330]

Gene Family (Interpro ID)

IPR000845  Nucleoside phosphorylase
IPR018017  Nucleoside phosphorylase, family 1
IPR010059  Uridine phosphorylase, eukaryotic

Link to Pubmed  (Pubmed ID)

752472
7488099
11278417
11807789
12036313
12084455
12115385
12477932
14702039
15489334
16798057
18457437
19291308
19714313
20856879
21906983
22632162
22939629

Gene Ontology  (GO ID)

Biological Process

GO:0042149  cellular response to glucose starvation
GO:0055086  nucleobase, nucleoside and nucleotide metabolic process
GO:0006139  nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0009166  nucleotide catabolic process
GO:0006206  pyrimidine base metabolic process
GO:0046135  pyrimidine nucleoside catabolic process
GO:0043097  pyrimidine nucleoside salvage
GO:0044206  UMP salvage
GO:0046108  uridine metabolic process

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0004850  uridine phosphorylase activity