vitronectin

jump to detail

Synonym

VTN, VNT, Vitronectin precursor, S-protein, VN, vitronectin, Serum-spreading factor, V75, somatomedin B

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:8.30

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:17.60

artery/aorta:-

vein:66.60

lymphnode:-

peripheral blood:-

spleen:18.90

thymus:12.90

bone marrow:-

adipose:-

bone:-

skin:4.80

GeneChip

cerebrum:4.53

cerebellum:4.63

brain stem:4.63

corpus callosum/glia:4.35

pineal gland:-

peripheral nerve:4.20

spine:4.32

retina:-

eye:-

artery/aorta:4.90

vein:4.81

lymphnode:4.65

peripheral blood:-

spleen:4.31

thymus:4.34

bone marrow:4.47

adipose:4.80

bone:-

skin:4.83

CAGE

cerebrum:0.03

cerebellum:-

brain stem:0

corpus callosum/glia:0

pineal gland:0

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:0

vein:0.18

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0.23

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.58

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.35

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:100.20

placenta:18.20

prostate:56.30

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:17

liver/hepato:-

lung:44

bladder:-

kidney:52

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:9.30

salivary:-

GeneChip

uterus:4.46

placenta:5.15

prostate:4.33

ovary:4.58

testis:4.57

heart:5.14

muscle:4.40

esophagus:4.35

stomach:4.62

intestine:4.77

colon:4.48

liver/hepato:10.97

lung:4.60

bladder:-

kidney:4.81

pituitary:4.46

thyroid/parathyroid:4.26

adrenal gland:6.19

pancreas:5.14

breast:4.27

salivary:4.44

CAGE

uterus:0

placenta:0

prostate:0

ovary:0

testis:0

heart:0.33

muscle:0

esophagus:0

stomach:-

intestine:0.21

colon:0.08

liver/hepato:4.52

lung:0

bladder:0

kidney:0

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:1.61

ovary:0.76

testis:2.59

heart:3.80

muscle:0.01

esophagus:-

stomach:-

intestine:-

colon:0.23

liver/hepato:10.82

lung:0.92

bladder:-

kidney:0.93

pituitary:-

thyroid/parathyroid:0.09

adrenal gland:1.00

pancreas:-

breast:0.15

salivary:-

IDs

Refseq ID	NM_000638
Gene ID	7448
Unigene ID	Hs.22575
Probe set ID	204534_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000255604
GTEx ID	ENSG00000255604

Orthologous Gene

Mouse[2]	NM_011707
Rat [0]

Chromosomal Region

17q11.2 [26,694,297 - 26,700,110]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001212	Somatomedin B
IPR020436	Somatomedin B, chordata

Gene Ontology (GO ID)

Biological Process

GO:0007155	cell adhesion
GO:0033627	cell adhesion mediated by integrin
GO:0007160	cell-matrix adhesion
GO:0030198	extracellular matrix organization
GO:0006955	immune response
GO:0045087	innate immune response
GO:0030195	negative regulation of blood coagulation
GO:0010951	negative regulation of endopeptidase activity
GO:0010811	positive regulation of cell-substrate adhesion
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0032092	positive regulation of protein binding
GO:0048260	positive regulation of receptor-mediated endocytosis
GO:0014911	positive regulation of smooth muscle cell migration
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0030449	regulation of complement activation

Cellular Component

GO:0071062	alphav-beta3 integrin-vitronectin complex
GO:0031012	extracellular matrix
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005578	proteinaceous extracellular matrix

Molecular Function

GO:0050840	extracellular matrix binding
GO:0008201	heparin binding
GO:0005178	integrin binding
GO:0030247	polysaccharide binding
GO:0005515	protein binding
GO:0005044	scavenger receptor activity

vitronectin

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function