aldehyde dehydrogenase 5 family, member A1

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Synonym

SSADH, SSDH, ALDH5A1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:39.10 cerebellum:25.20 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:92 spine:- retina:- eye:23.50 artery/aorta:- vein:- lymphnode:101.10 peripheral blood:- spleen:37.80 thymus:64.40 bone marrow:19.70 adipose:40.30 bone:- skin:33.60
GeneChip cerebrum:5.30 cerebellum:5.16 brain stem:4.99 corpus callosum/glia:5.10 pineal gland:- peripheral nerve:4.72 spine:5.21 retina:- eye:- artery/aorta:4.66 vein:4.83 lymphnode:4.77 peripheral blood:- spleen:4.89 thymus:5.31 bone marrow:4.84 adipose:4.71 bone:- skin:4.75
CAGE cerebrum:3.89 cerebellum:- brain stem:3.44 corpus callosum/glia:3.46 pineal gland:3.67 peripheral nerve:- spine:3.71 retina:- eye:- artery/aorta:2.43 vein:3.64 lymphnode:2.91 peripheral blood:- spleen:2.28 thymus:4.13 bone marrow:- adipose:2.63 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:3.60 prostate:11.30 ovary:37.30 testis:21.60 heart:25.50 muscle:40.20 esophagus:- stomach:- intestine:- colon:17     liver/hepato:42.20        lung:19.60    bladder:- kidney:228.70 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:18.60 salivary:-
GeneChip uterus:4.55 placenta:4.79 prostate:4.52 ovary:4.84 testis:4.31 heart:4.83 muscle:5.19 esophagus:4.68 stomach:4.56 intestine:4.75 colon:4.46 liver/hepato:5.95 lung:4.64 bladder:- kidney:5.18 pituitary:4.72 thyroid/parathyroid:5.07 adrenal gland:4.66 pancreas:4.81 breast:4.81 salivary:4.44
CAGE uterus:2.44 placenta:1.43 prostate:2.48 ovary:2.31 testis:2.63 heart:2.77 muscle:3.45 esophagus:2.23 stomach:- intestine:2.71 colon:3.09     liver/hepato:3.69    lung:2.73 bladder:2.12 kidney:2.55 pituitary:2.41 thyroid/parathyroid:2.92 adrenal gland:- pancreas:3.02 breast:2.02 salivary:2.12
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:0.00 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.20        lung:0.00    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.14 adrenal gland:0.20 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_170740
Gene ID 7915
Unigene ID Hs.371723
Probe set ID 203609_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000112294
GTEx ID ENSG00000112294

Orthologous Gene

Mouse[2]  NM_172532
Rat[2]  NM_172532

Chromosomal Region

6p22.3  [24,495,080  -  24,537,435]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

6470007
7814412
9059628
9683595
11243727
11901270
12208142
12477932
12629812
14574404
14635103
14981524
15037717
15489334
15642443
16199352
16406321
16786440
17457693
17913586
18029348
18457437
18505418
19086053
19300440
19343046
19667317
20201926
20301374
20363598
20379614
20445195
20659789
20877624
21438145
22001757
22437753
22939629
23516105
23825041
23926001
24327614
24722188

Gene Ontology  (GO ID)

Biological Process

GO:0006083  acetate metabolic process
GO:0007417  central nervous system development
GO:0006681  galactosylceramide metabolic process
GO:0009450  gamma-aminobutyric acid catabolic process
GO:0006006  glucose metabolic process
GO:0006678  glucosylceramide metabolic process
GO:0006536  glutamate metabolic process
GO:0006541  glutamine metabolic process
GO:0006749  glutathione metabolic process
GO:0006650  glycerophospholipid metabolic process
GO:0042135  neurotransmitter catabolic process
GO:0007269  neurotransmitter secretion
GO:0009791  post-embryonic development
GO:0051289  protein homotetramerization
GO:0022904  respiratory electron transport chain
GO:0046459  short-chain fatty acid metabolic process
GO:0006105  succinate metabolic process
GO:0007268  synaptic transmission

Cellular Component

GO:0005759  mitochondrial matrix
GO:0005739  mitochondrion

Molecular Function

GO:0042803  protein homodimerization activity
GO:0004777  succinate-semialdehyde dehydrogenase activity
GO:0009013  succinate-semialdehyde dehydrogenase [NAD(P)+] activity