calcitonin-related polypeptide alpha

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Synonym

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:378.10

cerebellum:151.10

brain stem:-

corpus callosum/glia:1516.40

pineal gland:-

peripheral nerve:153.40

spine:336.90

retina:474.60

eye:229.20

artery/aorta:1348.90

vein:1199.70

lymphnode:495.40

peripheral blood:819.80

spleen:548.30

thymus:412.30

bone marrow:747.90

adipose:524.30

bone:601.40

skin:441.60

GeneChip

cerebrum:4.90

cerebellum:4.91

brain stem:4.90

corpus callosum/glia:5.01

pineal gland:-

peripheral nerve:4.92

spine:4.83

retina:-

eye:-

artery/aorta:4.87

vein:5.21

lymphnode:4.70

peripheral blood:-

spleen:4.63

thymus:4.73

bone marrow:4.97

adipose:4.85

bone:-

skin:4.93

CAGE

cerebrum:0.14

cerebellum:-

brain stem:0.12

corpus callosum/glia:0

pineal gland:4.64

peripheral nerve:-

spine:0.54

retina:-

eye:-

artery/aorta:0.18

vein:0.18

lymphnode:0

peripheral blood:-

spleen:1.67

thymus:0.37

bone marrow:-

adipose:0.14

bone:-

skin:-

RNA-seq

cerebrum:0

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.26

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.07

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:419.20

placenta:291.40

prostate:304.10

ovary:186.30

testis:238

heart:255.40

muscle:60.30

esophagus:-

stomach:297.40

intestine:810

colon:330.70

liver/hepato:158.30

lung:347

bladder:1130.50

kidney:311.90

pituitary:232

thyroid/parathyroid:491.20

adrenal gland:609.40

pancreas:213.40

breast:297.40

salivary:-

GeneChip

uterus:4.74

placenta:5.18

prostate:4.69

ovary:4.84

testis:4.62

heart:4.94

muscle:4.99

esophagus:4.76

stomach:4.90

intestine:4.87

colon:5.09

liver/hepato:4.89

lung:4.92

bladder:-

kidney:5.40

pituitary:4.65

thyroid/parathyroid:6.30

adrenal gland:4.76

pancreas:5.07

breast:4.78

salivary:4.93

CAGE

uterus:0

placenta:0

prostate:0.81

ovary:0.07

testis:0.04

heart:0.83

muscle:0.13

esophagus:0

stomach:-

intestine:0

colon:0.04

liver/hepato:1.93

lung:0.42

bladder:0.40

kidney:1.86

pituitary:0.24

thyroid/parathyroid:3.39

adrenal gland:-

pancreas:0

breast:0.55

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.09

ovary:0.02

testis:0.02

heart:0.05

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0.20

liver/hepato:3.14

lung:0.44

bladder:-

kidney:2.47

pituitary:-

thyroid/parathyroid:2.01

adrenal gland:0.02

pancreas:-

breast:0

salivary:-

IDs

Refseq ID	NM_001741
Gene ID	796
Unigene ID	Hs.370581
Probe set ID	210727_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000110680
GTEx ID	ENSG00000110680

Orthologous Gene

Mouse[2]	NM_001033954, NM_007587
Rat [0]

Chromosomal Region

11p15.2 [14,988,214 - 14,993,900]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

LRG_13 [5,001 - 10,618]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001693	Calcitonin peptide-like
IPR000443	Pro-islet amyloid polypeptide
IPR015476	Procalcitonin gene related peptide, proCGRP
IPR021118	Procalcitonin, alpha type
IPR021117	Procalcitonin-like
IPR021116	Procalcitonin/adrenomedullin

Gene Ontology (GO ID)

Biological Process

GO:0007190	activation of adenylate cyclase activity
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway
GO:0032147	activation of protein kinase activity
GO:0007568	aging
GO:0007267	cell-cell signaling
GO:0051480	cytosolic calcium ion homeostasis
GO:0050965	detection of temperature stimulus involved in sensory perception of pain
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0051482	elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
GO:0007566	embryo implantation
GO:0043542	endothelial cell migration
GO:0001935	endothelial cell proliferation
GO:0007631	feeding behavior
GO:0002031	G-protein coupled receptor internalization
GO:0006954	inflammatory response
GO:0007159	leukocyte adhesion
GO:0002548	monocyte chemotaxis
GO:0045776	negative regulation of blood pressure
GO:0045779	negative regulation of bone resorption
GO:0010523	negative regulation of calcium ion transport into cytosol
GO:0031645	negative regulation of neurological system process
GO:0030279	negative regulation of ossification
GO:0045671	negative regulation of osteoclast differentiation
GO:0045986	negative regulation of smooth muscle contraction
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure
GO:0007218	neuropeptide signaling pathway
GO:0045762	positive regulation of adenylate cyclase activity
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0032730	positive regulation of interleukin-1 alpha production
GO:0032757	positive regulation of interleukin-8 production
GO:0045651	positive regulation of macrophage differentiation
GO:0045778	positive regulation of ossification
GO:0045909	positive regulation of vasodilation
GO:0006468	protein amino acid phosphorylation
GO:0031623	receptor internalization
GO:0008217	regulation of blood pressure
GO:0002027	regulation of heart rate
GO:0050727	regulation of inflammatory response
GO:0009408	response to heat
GO:0048265	response to pain
GO:0001944	vasculature development
GO:0042311	vasodilation
GO:0001984	vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure

Cellular Component

GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0043195	terminal button

Molecular Function

GO:0031716	calcitonin receptor binding
GO:0005179	hormone activity
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0005102	receptor binding

calcitonin-related polypeptide alpha

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function