PDZ domain containing 3

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Synonym

Intestinal and kidney-enriched PDZ protein, Protein DLNB27, PDZD3, PDZ domain containing 3, PDZ domain-containing protein 2, FLJ22756, IKEPP, PDZ domain containing 2, PDZ domain-containing protein 3, PDZK2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:7.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.18 vein:0.18 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:21.20 intestine:194.40 colon:17     liver/hepato:-        lung:-    bladder:- kidney:197.50 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:0 placenta:0 prostate:0.08 ovary:0.14 testis:0.04 heart:0 muscle:0 esophagus:0 stomach:- intestine:3.79 colon:3.34     liver/hepato:0.36    lung:0 bladder:0 kidney:2.11 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.17 ovary:0.00 testis:0.08 heart:0 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0    bladder:- kidney:1.15 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.09 salivary:-

Gene Information

IDs

Refseq ID NR_033122
Gene ID 79849
Unigene ID Hs.374726
Probe set ID -
Ensembl ID -
GTEx ID -

Orthologous Gene

Mouse [0]  
Rat [0]  

Chromosomal Region

11q23.3  [119,056,166  -  119,060,932]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1553237
11950846
12477932
12615054
14702039
15489334
15523054
15553237
16344560
19088451
22627094
22884631

Gene Ontology  (GO ID)

Biological Process

GO:0019934  cGMP-mediated signaling
GO:0006811  ion transport
GO:0030827  negative regulation of cGMP biosynthetic process
GO:0031283  negative regulation of guanylate cyclase activity
GO:0007168  receptor guanylyl cyclase signaling pathway
GO:0009636  response to toxin
GO:0006833  water transport

Cellular Component

GO:0045177  apical part of cell
GO:0005903  brush border
GO:0005829  cytosol
GO:0035003  subapical complex

Molecular Function

GO:0030251  guanylate cyclase inhibitor activity
GO:0008200  ion channel inhibitor activity
GO:0005515  protein binding
GO:0008022  protein C-terminus binding