Rho family GTPase 2

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Synonym

Rho7, ARHN, Rnd2, RHO7, Rho-related GTP-binding protein RhoN, RhoN, Rho family GTPase 2, RND2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:22.50 cerebellum:12.60 brain stem:- corpus callosum/glia:58.30 pineal gland:148.30 peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:9.60
GeneChip cerebrum:7.34 cerebellum:7.09 brain stem:8.12 corpus callosum/glia:7.16 pineal gland:- peripheral nerve:6.36 spine:7.87 retina:- eye:- artery/aorta:5.58 vein:6.21 lymphnode:5.66 peripheral blood:- spleen:5.65 thymus:5.03 bone marrow:5.80 adipose:5.84 bone:- skin:5.51
CAGE cerebrum:2.37 cerebellum:- brain stem:3.58 corpus callosum/glia:2.70 pineal gland:1.72 peripheral nerve:- spine:3.13 retina:- eye:- artery/aorta:0.79 vein:0.34 lymphnode:0.37 peripheral blood:- spleen:0 thymus:0.33 bone marrow:- adipose:0.14 bone:- skin:-
RNA-seq cerebrum:3.56 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.55 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.52 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:45.10 ovary:- testis:43.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:14.70    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.49 placenta:5.71 prostate:5.22 ovary:5.60 testis:8.24 heart:6 muscle:5.87 esophagus:5.78 stomach:5.90 intestine:5.94 colon:6.18 liver/hepato:6.13 lung:5.92 bladder:- kidney:5.79 pituitary:6.55 thyroid/parathyroid:6.25 adrenal gland:5.75 pancreas:6.09 breast:5.49 salivary:5.99
CAGE uterus:1.20 placenta:0 prostate:1.19 ovary:1.33 testis:3.25 heart:0.78 muscle:0.09 esophagus:1.08 stomach:- intestine:0.69 colon:0.56     liver/hepato:1.16    lung:0.45 bladder:1.21 kidney:0.27 pituitary:1.49 thyroid/parathyroid:2.29 adrenal gland:- pancreas:0 breast:0 salivary:0.36
RNA-seq uterus:- placenta:- prostate:1.73 ovary:2.57 testis:4.07 heart:0.21 muscle:0.14 esophagus:- stomach:- intestine:- colon:1.89     liver/hepato:2.42        lung:0.57    bladder:- kidney:0.51 pituitary:- thyroid/parathyroid:4.30 adrenal gland:1.01 pancreas:- breast:0.81 salivary:-

Gene Information

IDs

Refseq ID NM_005440
Gene ID 8153
Unigene ID Hs.603111
Probe set ID 213467_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000108830
GTEx ID ENSG00000108830

Orthologous Gene

Mouse[1]  NM_009708
Rat[1]  NM_001010953

Chromosomal Region

17q21.31  [41,177,258  -  41,184,057]

Gene Family (Interpro ID)

IPR013753  Ras
IPR001806  Ras GTPase
IPR020849  Ras small GTPase
IPR003579  Ras small GTPase, Rab type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR003578  Small GTPase, Rho type

Link to Pubmed  (Pubmed ID)

1909153
8889548
8938427
9531558
11931639
11940653
12244061
12477932
12590651
12730235
12842009
14702039
14732713
15489334
16189514
16311049
16481321
21989022
22807448

Gene Ontology  (GO ID)

Biological Process

GO:0006184  GTP catabolic process
GO:0007165  signal transduction
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0002080  acrosomal membrane
GO:0005769  early endosome

Molecular Function

GO:0005525  GTP binding
GO:0003924  GTPase activity
GO:0005515  protein binding
GO:0047485  protein N-terminus binding