sorting nexin family member 27

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Synonym

SNX27, MGC126873, MGC126871, sorting nexin family member 27, Sorting nexin-27, MGC20471, MY014, KIAA0488

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:68.70 cerebellum:50.40 brain stem:- corpus callosum/glia:29.20 pineal gland:296.70 peripheral nerve:- spine:- retina:474.60 eye:52.90 artery/aorta:- vein:- lymphnode:70.80 peripheral blood:54.70 spleen:18.90 thymus:38.70 bone marrow:39.40 adipose:121 bone:- skin:33.60
GeneChip cerebrum:7.65 cerebellum:7.44 brain stem:7.51 corpus callosum/glia:7.42 pineal gland:- peripheral nerve:7.38 spine:7.38 retina:- eye:- artery/aorta:7.08 vein:7.18 lymphnode:6.94 peripheral blood:- spleen:7.32 thymus:6.49 bone marrow:7.34 adipose:6.74 bone:- skin:6.68
CAGE cerebrum:3.51 cerebellum:- brain stem:3.20 corpus callosum/glia:3.28 pineal gland:3.40 peripheral nerve:- spine:3.17 retina:- eye:- artery/aorta:2.12 vein:2.35 lymphnode:2.08 peripheral blood:- spleen:2.53 thymus:1.88 bone marrow:- adipose:2.61 bone:- skin:-
RNA-seq cerebrum:3.76 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.40 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.15 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:91.10 prostate:22.50 ovary:37.30 testis:38.90 heart:25.50 muscle:80.40 esophagus:342.80 stomach:21.20 intestine:- colon:229     liver/hepato:21.10        lung:58.70    bladder:- kidney:114.40 pituitary:116 thyroid/parathyroid:- adrenal gland:152.40 pancreas:97.80 breast:27.90 salivary:-
GeneChip uterus:7.18 placenta:7.04 prostate:7.20 ovary:6.87 testis:6.64 heart:7.06 muscle:7.18 esophagus:7 stomach:7.22 intestine:6.72 colon:7.20 liver/hepato:6.99 lung:7.12 bladder:- kidney:7.73 pituitary:7.22 thyroid/parathyroid:6.94 adrenal gland:6.82 pancreas:6.68 breast:7.09 salivary:6.82
CAGE uterus:2.81 placenta:2.91 prostate:2.87 ovary:2.64 testis:2.96 heart:2.49 muscle:2.41 esophagus:2.41 stomach:- intestine:2.05 colon:2.36     liver/hepato:2.28    lung:2.47 bladder:3.08 kidney:3.10 pituitary:2.76 thyroid/parathyroid:2.42 adrenal gland:- pancreas:2.34 breast:2.02 salivary:2.22
RNA-seq uterus:- placenta:- prostate:3.84 ovary:3.29 testis:3.27 heart:2.75 muscle:3.40 esophagus:- stomach:- intestine:- colon:3.02     liver/hepato:2.29        lung:2.77    bladder:- kidney:3.63 pituitary:- thyroid/parathyroid:2.95 adrenal gland:2.54 pancreas:- breast:2.81 salivary:-

Gene Information

IDs

Refseq ID NM_030918
Gene ID 81609
Unigene ID Hs.192326
Probe set ID 221006_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000143376
GTEx ID ENSG00000143376

Orthologous Gene

Mouse[2]  NM_001082484, NM_029721
Rat[2]  NM_001110151, NM_152847

Chromosomal Region

1q21.3  [151,584,541  -  151,671,567]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
9455484
11485546
12461558
12477932
14702039
15121882
15466885
16710414
17351151
17577583
17644068
17828261
18029348
18690037
19322201
19555689
19615732
20379614
20733053
21139048
21300787
21303929
21602791
21890473
21906983
21926430
21988832
22411990
23000965
23536889
23563491
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0008333  endosome to lysosome transport
GO:0016197  endosome transport
GO:0001770  establishment of natural killer cell polarity
GO:0006886  intracellular protein transport
GO:0007165  signal transduction

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005769  early endosome
GO:0031901  early endosome membrane
GO:0001772  immunological synapse
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0030904  retromer complex
GO:0071203  WASH complex

Molecular Function

GO:0032266  phosphatidylinositol 3-phosphate binding
GO:0005515  protein binding